| Gene Symbol | CTSA |
|---|---|
| Entrez Gene | 5476 |
| Alt Symbol | GLB2, GSL, NGBE, PPCA, PPGB |
| Species | Human |
| Gene Type | protein-coding |
| Description | cathepsin A |
| Other Description | beta-galactosidase 2|beta-galactosidase protective protein|carboxypeptidase C|carboxypeptidase L|carboxypeptidase Y-like kininase|carboxypeptidase-L|deamidase|lysosomal carboxypeptidase A|lysosomal protective protein|protective protein cathepsin A|urinary kininase |
| Swissprots | Q561W6 Q5JZH1 Q9BW68 B2R798 P10619 Q9BR08 Q96KJ2 |
| Accessions | AAM09560 CCQ43096 EAW75788 EAW75789 P10619 AB209705 BAD92942 AF086236 AK055177 AK097786 AK172808 AK304536 BAG65336 AK307701 AK312898 BAG35745 BC000597 AAH00597 BC093009 AAH93009 DA029446 DQ891935 ABM82861 DQ895122 ABM86048 M22960 AAA36476 NM_000308 NP_000299 NM_001127695 NP_001121167 NM_001167594 NP_001161066 |
| Function | Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins. {ECO:0000269|PubMed:1907282}. |
| Subcellular Location | Lysosome. |
| Top Pathways | Lysosome, Renin-angiotensin system |