| Gene Symbol | IL6 |
|---|---|
| Entrez Gene | 100860785 |
| Alt Symbol | IL-6 |
| Species | Goat |
| Gene Type | protein-coding |
| Description | interleukin 6 (interferon, beta 2) |
| Other Description | interleukin-6 |
| Swissprots | Q28319 |
| Accessions | Q28319 D86569 BAA13118 HM565937 ADP09351 XM_005679035 XP_005679092 NM_001285640 NP_001272569 |
| Function | Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted. |
| Top Pathways | Inflammatory bowel disease (IBD), Cytokine-cytokine receptor interaction, Rheumatoid arthritis, Toll-like receptor signaling pathway, Jak-STAT signaling pathway |
Recombinant Goat Interleukin-6(IL6) - CSB-YP631708GO CSB-EP631708GO CSB-BP631708GO CSB-MP631708GO from Cusabio
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Interleukin-6 (IL6), Recombinant Protein - MBS1433606 from MyBioSource
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