| Gene Symbol | ATP1B3 |
|---|---|
| Entrez Gene | 483 |
| Alt Symbol | ATPB-3, CD298 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, Na+/K+ transporting, beta 3 polypeptide |
| Other Description | Na, K-ATPase beta-3 polypeptide|sodium pump subunit beta-3|sodium-potassium ATPase subunit beta 3 (non-catalytic)|sodium/potassium-dependent ATPase beta-3 subunit|sodium/potassium-dependent ATPase subunit beta-3|sodium/potassium-transporting ATPase beta-3 chain|sodium/potassium-transporting ATPase subunit beta-3 |
| Swissprots | P54709 B7Z1N7 |
| Accessions | AAB61713 EAW78982 EAW78983 EAW78984 EAW78985 EAW78986 EAW78987 EAW78988 EAW78989 P54709 AK094673 AK131061 AK293697 BAH11573 AY946018 AAX55913 BC001469 BC011835 AAH11835 BI462090 U51478 AAC50665 NM_001679 NP_001670 |
| Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:17081065}; Single-pass type II membrane protein {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Top Pathways | Salivary secretion, Cardiac muscle contraction, cAMP signaling pathway, Aldosterone-regulated sodium reabsorption, Thyroid hormone synthesis |