Gene Symbol | ATP1B3 |
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Entrez Gene | 483 |
Alt Symbol | ATPB-3, CD298 |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, Na+/K+ transporting, beta 3 polypeptide |
Other Description | Na, K-ATPase beta-3 polypeptide|sodium pump subunit beta-3|sodium-potassium ATPase subunit beta 3 (non-catalytic)|sodium/potassium-dependent ATPase beta-3 subunit|sodium/potassium-dependent ATPase subunit beta-3|sodium/potassium-transporting ATPase beta-3 chain|sodium/potassium-transporting ATPase subunit beta-3 |
Swissprots | P54709 B7Z1N7 |
Accessions | AAB61713 EAW78982 EAW78983 EAW78984 EAW78985 EAW78986 EAW78987 EAW78988 EAW78989 P54709 AK094673 AK131061 AK293697 BAH11573 AY946018 AAX55913 BC001469 BC011835 AAH11835 BI462090 U51478 AAC50665 NM_001679 NP_001670 |
Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:17081065}; Single-pass type II membrane protein {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Top Pathways | Salivary secretion, Cardiac muscle contraction, cAMP signaling pathway, Aldosterone-regulated sodium reabsorption, Thyroid hormone synthesis |
Na + /K + -ATPase β3 siRNA (h) - sc-62002 from Santa Cruz Biotechnology
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Na + /K + -ATPase β3 shRNA Plasmid (h) - sc-62002-SH from Santa Cruz Biotechnology
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Na + /K + -ATPase β3 shRNA (h) Lentiviral Particles - sc-62002-V from Santa Cruz Biotechnology
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ATPase Na+/K+ beta 3 RNAi - H00000483-R02 from Novus Biologicals
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MISSION® esiRNA - EHU111141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3685 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3685 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06755 from Sigma-Aldrich
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ATP1B3 siRNA (Human) - CRH0339 from Cohesion Biosciences
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ATP1B3 - MBS8202217 from MyBioSource
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shRNA set against Human ATP1B3(NM_001679.2) - SHG081541 from Creative biogene
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Human ATP1B3 siRNA - orb260841 from Biorbyt
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ATP1B3 shRNA Plasmid (Human) - CHH0339 from Cohesion Biosciences
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ATP1B3 miRNA 3'UTR clone - MiUTR1H-00681 from Creative biogene
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