ACVR1

Gene Symbol	ACVR1
Entrez Gene	90
Alt Symbol	ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
Species	Human
Gene Type	protein-coding
Description	activin A receptor, type I
Other Description	TGF-B superfamily receptor type I|activin A receptor, type II-like kinase 2|activin receptor type I|activin receptor type-1|activin receptor-like kinase 2|hydroxyalkyl-protein kinase|serine/threonine-protein kinase receptor R1
Swissprots	Q04771
Accessions	AAY15094 AAY24272 ADL14509 AJF45349 CAA02405 CAZ91465 CBX47654 EAX11438 EAX11439 EAX11440 EAX11441 EAX11442 EAX11443 Q04771 AK297765 BAG60113 AK313630 BC033867 AAH33867 BC036748 DA796090 L02911 AAA36614 Z22534 CAA80256 XM_005246939 XP_005246996 XM_005246940 XP_005246997 XM_006712825 XP_006712888 XM_011512106 XP_011510408 XM_011512107 XP_011510409 XM_011512108 XP_011510410 NM_001105 NP_001096 NM_001111067 NP_001104537
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells.
Top Pathways	Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Activin Receptor Type IA (mutated Q207 D) protein fragment - ab190988 from Abcam Category Protein Prices $521.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human Activin Receptor Type IA (mutated Q207 E) protein fragment - ab195114 from Abcam Category Protein Prices $521.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human Activin Receptor Type IA (mutated R206 H) protein fragment - ab167922 from Abcam Category Protein Prices $239.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Active human Activin Receptor Type IA protein fragment - ab84539 from Abcam Category Protein Prices $302.00, $352.00, $1,845.00 Sizes 5 µg, 10 µg, 100 µg Source Baculovirus infected sf9 cells Species Human

Human Activin Receptor Type IA full length protein - ab132044 from Abcam Category Protein Source Wheat germ Species Human

Human Activin Receptor Type IA protein fragment - ab157845 from Abcam Category Protein Source Wheat germ Species Human

Activin Receptor Type IA protein (Fc Chimera) - ab83922 from Abcam Category Protein Source HEK 293 cells Species Human

ALK2 / ACVR1 Antibody Blocking Peptide - LS-E2760 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALK2 / ACVR1 Antibody Blocking Peptide - LS-E2714 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALK2 / ACVR1 Antibody Blocking Peptide - LS-E8690 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALK2 / ACVR1 Antibody Blocking Peptide - LS-E8691 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALK2 / ACVR1 Antibody Blocking Peptide - LS-E8689 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALK2 / ACVR1 Antibody Blocking Peptide - LS-E9276 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALK2 / ACVR1 Antibody Blocking Peptide - LS-E16526 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALK2 / ACVR1 Antibody Blocking Peptide - LS-E26539 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ALK2 / ACVR1 Antibody Blocking Peptide - LS-E30567 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Activin RIA/ALK-2/Activin Receptor Type 1 Recombinant Protein - H00000090-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Activin RIA/ALK-2/Activin Receptor Type 1 Protein - H00000090-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Activin RIA/ALK-2/Activin Receptor Type 1 Peptide - NBP1-76352PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

Activin RIA/ALK-2/Activin Receptor Type 1 Recombinant Protein - P4646 from Novus Biologicals Category Protein Prices $1,559.00 Sizes 100 µg Species Human

Activin RIA/ALK-2/Activin Receptor Type 1 Peptide - NBP1-76350PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

Activin RIA/ALK-2/Activin Receptor Type 1 Peptide - P2242 from Novus Biologicals Category Peptide Species Human

ACVR1-Antibody-Center-Blocking-peptide - BP13856c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Activin-Receptor-Type-IA-ACVR1-Antibody-Center-N99-Blocking-peptide - BP7101c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Activin-Receptor-Type-IA-ACVR1-Antibody-N-term-Blocking-peptide - BP7101b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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