Gene Symbol | GALNT18 |
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Entrez Gene | 374378 |
Alt Symbol | GALNACT18, GALNT15, GALNTL4, GalNAc-T15, GalNAc-T18 |
Species | Human |
Gene Type | protein-coding |
Description | polypeptide N-acetylgalactosaminyltransferase 18 |
Other Description | GalNAc-transferase 18|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 4|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4|galNAc-T-like protein 4|polypeptide GalNAc transferase 18|polypeptide GalNAc transferase-like protein 4|polypeptide N-acetylgalactosaminyltransferase-like protein 4|pp-GaNTase-like protein 4|protein-UDP acetylgalactosaminyltransferase-like protein 4|putative polypeptide N-acetylgalactosaminyltransferase-like protein 4 |
Swissprots | Q8NDY9 O95903 Q6P9A2 |
Accessions | EAW68545 Q6P9A2 AB078147 BAD93179 AF131852 AAD20062 AJ626724 CAF25035 AK055111 BAG51470 AK124690 BC037341 AAH37341 BC060864 AAH60864 CR627308 XM_006718224 XP_006718287 XM_006718225 XP_006718288 XM_011520068 XP_011518370 XM_011520069 XP_011518371 XM_011520070 XP_011518372 XM_011520071 XP_011518373 NM_198516 NP_940918 |
Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. {ECO:0000269|PubMed:22186971}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
GalNAc-TL4 CRISPR/Cas9 KO Plasmid (h) - sc-415682 from Santa Cruz Biotechnology
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GalNAc-TL4 HDR Plasmid (h) - sc-415682-HDR from Santa Cruz Biotechnology
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GalNAc-TL4 Double Nickase Plasmid (h) - sc-415682-NIC from Santa Cruz Biotechnology
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GalNAc-TL4 Double Nickase Plasmid (h2) - sc-415682-NIC-2 from Santa Cruz Biotechnology
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GalNAc-TL4 CRISPR Activation Plasmid (h) - sc-415682-ACT from Santa Cruz Biotechnology
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GalNAc-TL4 CRISPR Activation Plasmid (h2) - sc-415682-ACT-2 from Santa Cruz Biotechnology
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GalNAc-TL4 Lentiviral Activation Particles (h) - sc-415682-LAC from Santa Cruz Biotechnology
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GalNAc-TL4 Lentiviral Activation Particles (h2) - sc-415682-LAC-2 from Santa Cruz Biotechnology
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GalNAc-TL4 siRNA (h) - sc-96270 from Santa Cruz Biotechnology
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GalNAc-TL4 shRNA Plasmid (h) - sc-96270-SH from Santa Cruz Biotechnology
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GalNAc-TL4 shRNA (h) Lentiviral Particles - sc-96270-V from Santa Cruz Biotechnology
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GALNTL4 RNAi - H00374378-R01 from Novus Biologicals
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MISSION® esiRNA - EHU018511 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9117 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9117 from Sigma-Aldrich
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GALNT18 siRNA (Human) - CRJ7613 from Cohesion Biosciences
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GALNT18 - MBS8220075 from MyBioSource
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shRNA set against Human GALNTL4 (NM_198516.2) - SHH299137 from Creative biogene
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Human GALNT18 siRNA - orb278114 from Biorbyt
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GALNT18 shRNA Plasmid (Human) - CHJ7613 from Cohesion Biosciences
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GALNTL4 miRNA 3'UTR clone - MiUTR3H-14982 from Creative biogene
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