Gene Symbol | PCYT1A |
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Entrez Gene | 5130 |
Alt Symbol | CCTA, CT, CTA, CTPCT, PCYT1, SMDCRD |
Species | Human |
Gene Type | protein-coding |
Description | phosphate cytidylyltransferase 1, choline, alpha |
Other Description | CCT A|CCT-alpha|CT A|CTP:phosphocholine cytidylyltransferase A|choline-phosphate cytidylyltransferase A|phosphorylcholine transferase A |
Swissprots | P49585 A9LYK9 D3DXB1 Q86Y88 |
Accessions | ABX44666 EAW53655 EAW53662 P49585 AF088041 AK001567 AK129838 AK304534 BAG65334 AK309073 AK309300 AK313450 BAG36238 BC042043 BC046355 AAH46355 L28957 AAA72127 NM_005017 NP_005008 |
Function | Controls phosphatidylcholine synthesis. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form. {ECO:0000250}. |
Top Pathways | Choline metabolism in cancer, Glycerophospholipid metabolism |
CCT A CRISPR/Cas9 KO Plasmid (h) - sc-404021 from Santa Cruz Biotechnology
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CCT A HDR Plasmid (h) - sc-404021-HDR from Santa Cruz Biotechnology
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CCT A Double Nickase Plasmid (h) - sc-404021-NIC from Santa Cruz Biotechnology
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CCT A Double Nickase Plasmid (h2) - sc-404021-NIC-2 from Santa Cruz Biotechnology
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CCT A CRISPR Activation Plasmid (h) - sc-404021-ACT from Santa Cruz Biotechnology
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CCT A CRISPR Activation Plasmid (h2) - sc-404021-ACT-2 from Santa Cruz Biotechnology
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CCT A Lentiviral Activation Particles (h) - sc-404021-LAC from Santa Cruz Biotechnology
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CCT A Lentiviral Activation Particles (h2) - sc-404021-LAC-2 from Santa Cruz Biotechnology
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CCT A siRNA (h) - sc-40394 from Santa Cruz Biotechnology
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CCT A shRNA Plasmid (h) - sc-40394-SH from Santa Cruz Biotechnology
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CCT A shRNA (h) Lentiviral Particles - sc-40394-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU065801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16509 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16509 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02452 from Sigma-Aldrich
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PCYT1A siRNA (Human) - CRH3412 from Cohesion Biosciences
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PCYT1A RNAi - H00005130-R01 from Novus Biologicals
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shRNA set against Human PCYT1A(NM_005017.2) - SHR098574 from Creative biogene
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Human PCYT1A siRNA - orb263914 from Biorbyt
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PCYT1A shRNA Plasmid (Human) - CHH3412 from Cohesion Biosciences
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PCYT1A miRNA 3'UTR clone - MiUTR1H-07691 from Creative biogene
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