Gene Symbol | LANCL1 |
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Entrez Gene | 10314 |
Alt Symbol | GPR69A, p40 |
Species | Human |
Gene Type | protein-coding |
Description | LanC lantibiotic synthetase component C-like 1 (bacterial) |
Other Description | 40 kDa erythrocyte membrane protein|G protein-coupled receptor 69A|LanC (bacterial lantibiotic synthetase component C)-like 1|LanC (bacterial lantibiotic synthetase component)|lanC-like protein 1 |
Swissprots | O43813 |
Accessions | AAY14696 CAC21950 EAW70487 EAW70488 EAW70489 EAW70490 EAW70491 O43813 AK294674 BAG57838 AK309295 AK312381 BAG35299 BC007041 BC028685 AAH28685 BX473106 CR541777 CAG46576 DC321883 DC324843 DQ893780 ABM84706 Y11395 CAA72205 XM_005246243 XP_005246300 NM_001136574 NP_001130046 NM_001136575 NP_001130047 NM_006055 NP_006046 |
Function | May play a role in EPS8 signaling. Binds glutathione. {ECO:0000269|PubMed:19528316}. |
Subcellular Location | Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Note=Detected at the surface of Maurer's clefts in malaria-infected erythrocytes at late stages of parasite development. |
Tissue Specificity | Detected in erythrocytes, brain, kidney, testis, ovary, heart, lung, placenta and spleen (at protein level). Ubiquitous. Strongly expressed in brain, spinal cord, pituitary gland, kidney, heart, skeletal muscle, pancreas, ovary and testis. {ECO:0000269|PubMed:10944443, ECO:0000269|PubMed:15811525, ECO:0000269|PubMed:9512664}. |
LANCL1 CRISPR/Cas9 KO Plasmid (h) - sc-409776 from Santa Cruz Biotechnology
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LANCL1 HDR Plasmid (h) - sc-409776-HDR from Santa Cruz Biotechnology
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LANCL1 Double Nickase Plasmid (h) - sc-409776-NIC from Santa Cruz Biotechnology
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LANCL1 Double Nickase Plasmid (h2) - sc-409776-NIC-2 from Santa Cruz Biotechnology
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LANCL1 CRISPR Activation Plasmid (h) - sc-409776-ACT from Santa Cruz Biotechnology
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LANCL1 CRISPR Activation Plasmid (h2) - sc-409776-ACT-2 from Santa Cruz Biotechnology
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LANCL1 Lentiviral Activation Particles (h) - sc-409776-LAC from Santa Cruz Biotechnology
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LANCL1 Lentiviral Activation Particles (h2) - sc-409776-LAC-2 from Santa Cruz Biotechnology
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LANCL1 siRNA (h) - sc-94288 from Santa Cruz Biotechnology
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LANCL1 shRNA Plasmid (h) - sc-94288-SH from Santa Cruz Biotechnology
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LANCL1 shRNA (h) Lentiviral Particles - sc-94288-V from Santa Cruz Biotechnology
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LANCL1 RNAi - H00010314-R02 from Novus Biologicals
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MISSION® esiRNA - EHU035861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11542 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11542 from Sigma-Aldrich
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LANCL1 siRNA (Human) - CRH6988 from Cohesion Biosciences
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shRNA set against Human LANCL1 (NM_006055.2) - SHH328395 from Creative biogene
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LANCL1 shRNA Plasmid (Human) - CHH6988 from Cohesion Biosciences
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LANCL1 miRNA 3'UTR clone - MiUTR4H-TG04967 from Creative biogene
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