| Gene Symbol |
GOT2
|
| Entrez Gene |
100052607
|
| Alt Symbol |
-
|
| Species |
Horse
|
| Gene Type |
protein-coding
|
| Description |
glutamic-oxaloacetic transaminase 2, mitochondrial
|
| Other Description |
-
|
| Swissprots |
P08907
|
| Accessions |
XM_001495424 XP_001495474
|
| Function |
Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion matrix. Cell membrane {ECO:0000250}.
|
| Top Pathways |
Cysteine and methionine metabolism, Fat digestion and absorption, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Phenylalanine metabolism
|