Gene Symbol |
GOT2
|
Entrez Gene |
100052607
|
Alt Symbol |
-
|
Species |
Horse
|
Gene Type |
protein-coding
|
Description |
glutamic-oxaloacetic transaminase 2, mitochondrial
|
Other Description |
-
|
Swissprots |
P08907
|
Accessions |
XM_001495424 XP_001495474
|
Function |
Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). {ECO:0000250}.
|
Subcellular Location |
Mitochondrion matrix. Cell membrane {ECO:0000250}.
|
Top Pathways |
Cysteine and methionine metabolism, Fat digestion and absorption, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Phenylalanine metabolism
|