GOT2

Gene Symbol GOT2
Entrez Gene 100052607
Alt Symbol -
Species Horse
Gene Type protein-coding
Description glutamic-oxaloacetic transaminase 2, mitochondrial
Other Description -
Swissprots P08907
Accessions XM_001495424 XP_001495474
Function Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). {ECO:0000250}.
Subcellular Location Mitochondrion matrix. Cell membrane {ECO:0000250}.
Top Pathways Cysteine and methionine metabolism, Fat digestion and absorption, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Phenylalanine metabolism