Gene Symbol | POU5F2 |
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Entrez Gene | 134187 |
Alt Symbol | SPRM-1 |
Species | Human |
Gene Type | protein-coding |
Description | POU domain class 5, transcription factor 2 |
Other Description | POU domain, class 5, transcription factor 2|sperm 1 POU domain transcription factor |
Swissprots | Q6MZL7 Q15169 Q8N7G0 Q8N748 |
Accessions | EAW96016 Q8N7G0 AK098546 BAC05328 BC029532 AAH29532 BX641019 CAE46012 EU446850 ABZ92379 Z21965 CAA79976 NM_153216 NP_694948 |
Function | Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3'). May exert a regulatory function in meiotic events that are required for terminal differentiation of male germ cell (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00530}. |
Tissue Specificity | Expressed in skeletal and cardiac muscles, brain, heart and lung. Little or no detectable expression found in pancreas, kidney, liver or placenta. {ECO:0000269|PubMed:7908264}. |
Sprm-1 CRISPR/Cas9 KO Plasmid (h) - sc-409037 from Santa Cruz Biotechnology
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Sprm-1 HDR Plasmid (h) - sc-409037-HDR from Santa Cruz Biotechnology
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Sprm-1 Double Nickase Plasmid (h) - sc-409037-NIC from Santa Cruz Biotechnology
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Sprm-1 Double Nickase Plasmid (h2) - sc-409037-NIC-2 from Santa Cruz Biotechnology
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Sprm-1 CRISPR Activation Plasmid (h) - sc-409037-ACT from Santa Cruz Biotechnology
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Sprm-1 CRISPR Activation Plasmid (h2) - sc-409037-ACT-2 from Santa Cruz Biotechnology
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Sprm-1 Lentiviral Activation Particles (h) - sc-409037-LAC from Santa Cruz Biotechnology
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Sprm-1 Lentiviral Activation Particles (h2) - sc-409037-LAC-2 from Santa Cruz Biotechnology
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Sprm-1 siRNA (h) - sc-91619 from Santa Cruz Biotechnology
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Sprm-1 shRNA Plasmid (h) - sc-91619-SH from Santa Cruz Biotechnology
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Sprm-1 shRNA (h) Lentiviral Particles - sc-91619-V from Santa Cruz Biotechnology
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POU5F2 RNAi - H00134187-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN17188 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17188 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01648 from Sigma-Aldrich
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POU5F2 siRNA (Human) - CRJ5134 from Cohesion Biosciences
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shRNA set against Human POU5F2 (NM_153216.1) - SHH380160 from Creative biogene
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POU5F2 shRNA Plasmid (Human) - CHJ5134 from Cohesion Biosciences
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POU5F2 miRNA 3'UTR clone - MiUTR1H-03725 from Creative biogene
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