| Gene Symbol |
Cckar
|
| Entrez Gene |
100719593
|
| Alt Symbol |
CCK-AR, CCK1-R
|
| Species |
Guinea Pig
|
| Gene Type |
protein-coding
|
| Description |
cholecystokinin A receptor
|
| Other Description |
CCK-A receptor|Cholecystokinin receptor type A|Cholecystokinin-1 receptor
|
| Swissprots |
Q63931
|
| Accessions |
Q63931 XM_003467402 XP_003467450
|
| Function |
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|