Gene Symbol | TMEM165 |
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Entrez Gene | 55858 |
Alt Symbol | CDG2K, FT27, GDT1, TMPT27, TPARL |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 165 |
Other Description | TPA regulated locus|transmembrane protein PT27|transmembrane protein TPARL |
Swissprots | Q9BTN9 Q9NZ34 A8K3P8 B4DHW1 Q9HC07 |
Accessions | EAX05467 Q9HC07 AF132746 AAL75947 AF183409 AAG09678 AF220188 AAF67653 AK026163 AK027162 AK054712 BAG51414 AK055076 AK290663 BAF83352 AK295289 BAG58273 BC003545 AAH03545 BC104978 AAI04979 BC104980 AAI04981 BC107582 AAI07583 DA371259 HY089602 XM_011534394 XP_011532696 NM_018475 NP_060945 NR_073070 |
Function | May function as a calcium/proton transporter involved in calcium and in lysosomal pH homeostasis. Therefore, it may play an indirect role in protein glycosylation. {ECO:0000269|PubMed:22683087, ECO:0000269|PubMed:23569283}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Golgi apparatus, trans- Golgi network membrane. Lysosome membrane. Early endosome membrane. Late endosome membrane. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:22683087}. |
TMEM165 CRISPR/Cas9 KO Plasmid (h) - sc-412628 from Santa Cruz Biotechnology
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TMEM165 HDR Plasmid (h) - sc-412628-HDR from Santa Cruz Biotechnology
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TMEM165 Double Nickase Plasmid (h) - sc-412628-NIC from Santa Cruz Biotechnology
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TMEM165 Double Nickase Plasmid (h2) - sc-412628-NIC-2 from Santa Cruz Biotechnology
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TMEM165 CRISPR Activation Plasmid (h) - sc-412628-ACT from Santa Cruz Biotechnology
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TMEM165 CRISPR Activation Plasmid (h2) - sc-412628-ACT-2 from Santa Cruz Biotechnology
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TMEM165 Lentiviral Activation Particles (h) - sc-412628-LAC from Santa Cruz Biotechnology
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TMEM165 Lentiviral Activation Particles (h2) - sc-412628-LAC-2 from Santa Cruz Biotechnology
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TMEM165 siRNA (h) - sc-88889 from Santa Cruz Biotechnology
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TMEM165 shRNA Plasmid (h) - sc-88889-SH from Santa Cruz Biotechnology
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TMEM165 shRNA (h) Lentiviral Particles - sc-88889-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU037391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21534 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21534 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06425 from Sigma-Aldrich
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TMEM165 siRNA (Human) - CRJ0976 from Cohesion Biosciences
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TMEM165 - MBS8206171 from MyBioSource
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shRNA set against Human TMEM165 (NM_018475.4) - SHH429456 from Creative biogene
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Human TMEM165 siRNA - orb271477 from Biorbyt
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TMEM165 shRNA Plasmid (Human) - CHJ0976 from Cohesion Biosciences
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TMEM165 miRNA 3'UTR clone - MiUTR3H-13374 from Creative biogene
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