Gene Symbol | POLR1D |
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Entrez Gene | 51082 |
Alt Symbol | AC19, POLR1C, RPA16, RPA9, RPAC2, RPC16, RPO1-3, TCS2 |
Species | Human |
Gene Type | protein-coding |
Description | polymerase (RNA) I polypeptide D, 16kDa |
Other Description | DNA-directed RNA polymerase I subunit D|DNA-directed RNA polymerases I and III subunit RPAC2|RNA polymerases I and III subunit AC2 |
Swissprots | Q96BR3 Q5TBX2 Q9Y2S0 |
Accessions | EAX08415 EAX08416 Q9Y2S0 AF077044 AAD27777 AF131855 AK000623 AK097973 AK307356 AK311833 BAG34775 BC000889 AAH00889 BC006972 AAH06972 BC015319 AAH15319 BC018528 AAH18528 BC054519 BI253733 BQ004736 DB123903 DB455307 DB459107 DB518623 DR156229 HQ448674 ADQ33152 XM_005266412 XP_005266469 XM_005266414 XP_005266471 NM_001206559 NP_001193488 NM_015972 NP_057056 NM_152705 NP_689918 |
Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. |
Subcellular Location | Nucleus {ECO:0000250}. |
Top Pathways | Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism |
RPA16 CRISPR/Cas9 KO Plasmid (h) - sc-416274 from Santa Cruz Biotechnology
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RPA16 HDR Plasmid (h) - sc-416274-HDR from Santa Cruz Biotechnology
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RPA16 Double Nickase Plasmid (h) - sc-416274-NIC from Santa Cruz Biotechnology
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RPA16 Double Nickase Plasmid (h2) - sc-416274-NIC-2 from Santa Cruz Biotechnology
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RPA16 CRISPR Activation Plasmid (h) - sc-416274-ACT from Santa Cruz Biotechnology
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RPA16 CRISPR Activation Plasmid (h2) - sc-416274-ACT-2 from Santa Cruz Biotechnology
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RPA16 Lentiviral Activation Particles (h) - sc-416274-LAC from Santa Cruz Biotechnology
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RPA16 Lentiviral Activation Particles (h2) - sc-416274-LAC-2 from Santa Cruz Biotechnology
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RPA16 siRNA (h) - sc-38240 from Santa Cruz Biotechnology
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RPA16 shRNA Plasmid (h) - sc-38240-SH from Santa Cruz Biotechnology
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RPA16 shRNA (h) Lentiviral Particles - sc-38240-V from Santa Cruz Biotechnology
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POLR1D RNAi - H00051082-R01 from Novus Biologicals
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MISSION® esiRNA - EHU095661 from Sigma-Aldrich
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MISSION® esiRNA - EHU096161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17109 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17109 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09357 from Sigma-Aldrich
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POLR1D siRNA (Human) - CRH9504 from Cohesion Biosciences
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shRNA set against Human POLR1D (NM_015972.3) - SHH379356 from Creative biogene
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Human POLR1D siRNA - orb270006 from Biorbyt
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POLR1D shRNA Plasmid (Human) - CHH9504 from Cohesion Biosciences
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POLR1D miRNA 3'UTR clone - MiUTR3H-13011 from Creative biogene
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