| Gene Symbol | Rce1 |
|---|---|
| Entrez Gene | 309153 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | Ras converting CAAX endopeptidase 1 |
| Other Description | CAAX prenyl protease 2|FACE-2|RCE1 homolog, prenyl protein peptidase|RCE1 homolog, prenyl protein protease|farnesylated proteins-converting enzyme 2|prenyl protein-specific endoprotease 2 |
| Swissprots | B0BMW8 |
| Accessions | B0BMW8 EDM12412 EDM12413 BC087629 AAH87629 BC158593 AAI58594 XM_006230788 XP_006230850 XM_006230790 XP_006230852 XM_006230791 XP_006230853 XM_008760135 XP_008758357 XM_008760136 XP_008758358 NM_001100585 NP_001094055 |
| Function | Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (By similarity). {ECO:0000250}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | Terpenoid backbone biosynthesis |
CompoZr® Knockout ZFN Kit - CKOZFN61167 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND61167 from Sigma-Aldrich
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RCE1 siRNA (Rat) - CRR5186 from Cohesion Biosciences
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RCE1 - MBS8218666 from MyBioSource
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shRNA set against Rat RCE1 (NM_001100585.1) - SHH391284 from Creative biogene
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Rat RCE1 siRNA - orb300035 from Biorbyt
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RCE1 shRNA Plasmid (Rat) - CHR5186 from Cohesion Biosciences
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