| Gene Symbol |
GTF2H5
|
| Entrez Gene |
404672
|
| Alt Symbol |
C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTDA, bA120J8.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
general transcription factor IIH, polypeptide 5
|
| Other Description |
TFB5 ortholog|TFIIH basal transcription factor complex TTD-A subunit|TFIIH basal transcription factor complex TTDA subunit|general transcription factor IIH subunit 5
|
| Swissprots |
Q0P5V8 Q6ZYL4
|
| Accessions |
CAK32279 EAW47663 Q6ZYL4 AJ634743 CAG25512 AK024874 AK055106 AK129771 BC004568 BC038848 BC056906 AAH56906 BC060317 AAH60317 BQ004444 CN403888 EU446604 ABZ92133 U92024 U92025 NM_207118 NP_997001
|
| Function |
Component of the TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Necessary for the stability of the TFIIH complex and for the presence of normal levels of TFIIH in the cell. {ECO:0000269|PubMed:15220921}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:15220921}.
|
| Top Pathways |
Nucleotide excision repair, Basal transcription factors
|
![Western Blot: GTF2H5 Overexpression Lysate (Adult Normal) [NBL1-11392] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GTF2H5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8387_GTF2H5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11392-img0002.jpg)