Gene Symbol | ARPC1B |
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Entrez Gene | 10095 |
Alt Symbol | ARC41, p40-ARC, p41-ARC |
Species | Human |
Gene Type | protein-coding |
Description | actin related protein 2/3 complex, subunit 1B, 41kDa |
Other Description | ARP2/3 protein complex subunit p41|actin-related protein 2/3 complex subunit 1B|arp2/3 complex 41 kDa subunit |
Swissprots | Q9BU00 O15143 |
Accessions | EAL23882 EAW76677 EAW76678 EAW76679 EAW76680 O15143 AF006084 AAB64189 AK314818 BAG37341 AU143525 AY007111 BC002562 AAH02562 BC002988 AAH02988 BC007555 AAH07555 DQ892169 ABM83095 DQ895363 ABM86289 XM_006715825 XP_006715888 XM_006715826 XP_006715889 NM_005720 NP_005711 |
Function | Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Top Pathways | Pathogenic Escherichia coli infection, Fc gamma R-mediated phagocytosis, Bacterial invasion of epithelial cells, Salmonella infection, Regulation of actin cytoskeleton |
p41-ARCb CRISPR/Cas9 KO Plasmid (h) - sc-405027 from Santa Cruz Biotechnology
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p41-ARCb HDR Plasmid (h) - sc-405027-HDR from Santa Cruz Biotechnology
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p41-ARCb Double Nickase Plasmid (h) - sc-405027-NIC from Santa Cruz Biotechnology
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p41-ARCb Double Nickase Plasmid (h2) - sc-405027-NIC-2 from Santa Cruz Biotechnology
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p41-ARCb CRISPR Activation Plasmid (h) - sc-405027-ACT from Santa Cruz Biotechnology
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p41-ARCb CRISPR Activation Plasmid (h2) - sc-405027-ACT-2 from Santa Cruz Biotechnology
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p41-ARCb Lentiviral Activation Particles (h) - sc-405027-LAC from Santa Cruz Biotechnology
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p41-ARCb Lentiviral Activation Particles (h2) - sc-405027-LAC-2 from Santa Cruz Biotechnology
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p41-ARCb siRNA (h) - sc-62745 from Santa Cruz Biotechnology
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p41-ARCb shRNA Plasmid (h) - sc-62745-SH from Santa Cruz Biotechnology
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p41-ARCb shRNA (h) Lentiviral Particles - sc-62745-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU007891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3526 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3526 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01985 from Sigma-Aldrich
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ARPC1B siRNA (Human) - CRH6803 from Cohesion Biosciences
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ARPC1B - MBS8240325 from MyBioSource
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shRNA set against Human ARPC1B (NM_005720.3) - SHH240618 from Creative biogene
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Human ARPC1B siRNA - orb267305 from Biorbyt
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ARPC1B shRNA Plasmid (Human) - CHH6803 from Cohesion Biosciences
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ARPC1B miRNA 3'UTR clone - MiUTR3H-06656 from Creative biogene
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