Gene Symbol | UQCRB |
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Entrez Gene | 7381 |
Alt Symbol | MC3DN3, QCR7, QP-C, QPC, UQBC, UQBP, UQCR6, UQPC |
Species | Human |
Gene Type | protein-coding |
Description | ubiquinol-cytochrome c reductase binding protein |
Other Description | complex III subunit 7|complex III subunit VII|cytochrome b-c1 complex subunit 7|mitochondrial ubiquinone-binding protein|ubiquinol-cytochrome c reductase complex 14 kDa protein|ubiquinol-cytochrome c reductase, complex III subunit VI |
Swissprots | Q6FGD1 E5RJU0 P14927 |
Accessions | AAA60235 AAA60237 AAA60361 AAA60362 EAW91749 P14927 AI365233 AK295007 BAH11948 AK307085 AK311756 BAG34699 AV747179 BC005230 AAH05230 BC041005 BI547559 BU535281 CR542176 CAG46973 CR542196 CAG46993 M22348 AAA60238 M26700 AAA60236 X13585 CAA31926 NM_001199975 NP_001186904 NM_001254752 NP_001241681 NM_006294 NP_006285 NR_045639 |
Function | This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This component is involved in redox-linked proton pumping. |
Subcellular Location | Mitochondrion inner membrane. |
Top Pathways | Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
UQCRB CRISPR/Cas9 KO Plasmid (h) - sc-416506 from Santa Cruz Biotechnology
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UQCRB HDR Plasmid (h) - sc-416506-HDR from Santa Cruz Biotechnology
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UQCRB Double Nickase Plasmid (h) - sc-416506-NIC from Santa Cruz Biotechnology
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UQCRB Double Nickase Plasmid (h2) - sc-416506-NIC-2 from Santa Cruz Biotechnology
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UQCRB CRISPR Activation Plasmid (h) - sc-416506-ACT from Santa Cruz Biotechnology
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UQCRB CRISPR Activation Plasmid (h2) - sc-416506-ACT-2 from Santa Cruz Biotechnology
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UQCRB Lentiviral Activation Particles (h) - sc-416506-LAC from Santa Cruz Biotechnology
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UQCRB Lentiviral Activation Particles (h2) - sc-416506-LAC-2 from Santa Cruz Biotechnology
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UQCRB siRNA (h) - sc-77467 from Santa Cruz Biotechnology
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UQCRB shRNA Plasmid (h) - sc-77467-SH from Santa Cruz Biotechnology
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UQCRB shRNA (h) Lentiviral Particles - sc-77467-V from Santa Cruz Biotechnology
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UQCRB RNAi - H00007381-R01 from Novus Biologicals
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MISSION® esiRNA - EHU106011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22532 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22532 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04276 from Sigma-Aldrich
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UQCRB siRNA (Human) - CRH5050 from Cohesion Biosciences
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UQCRB - MBS8211291 from MyBioSource
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shRNA set against Human UQCRB (NM_006294.4) - SHH440924 from Creative biogene
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Human UQCRB siRNA - orb265552 from Biorbyt
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UQCRB shRNA Plasmid (Human) - CHH5050 from Cohesion Biosciences
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