| Gene Symbol |
IFNG
|
| Entrez Gene |
100860815
|
| Alt Symbol |
IFN-gamma
|
| Species |
Goat
|
| Gene Type |
protein-coding
|
| Description |
interferon, gamma
|
| Other Description |
interferon gamma|interferon-gamma
|
| Swissprots |
Q6E219 Q53ZM6 P79154
|
| Accessions |
P79154 AY304501 AAP68800 U34232 AAB38525 XM_005680208 XP_005680265 NM_001285682 NP_001272611
|
| Function |
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Released primarily from activated T lymphocytes.
|
| Top Pathways |
Proteasome, Inflammatory bowel disease (IBD), Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
|