| Gene Symbol | Ugt1a2 |
|---|---|
| Entrez Gene | 22236 |
| Alt Symbol | UDPGT 1-2, Ugt1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | UDP glucuronosyltransferase 1 family, polypeptide A2 |
| Other Description | UDP-glucuronosyltransferase 1 family, member 2|UDP-glucuronosyltransferase 1 family, polypeptide A2|UDP-glucuronosyltransferase 1-2|UDP-glucuronosyltransferase 1A2|UDPGT|UGT1*0|UGT1-02|UGT1.2|bilirubin specific|bilirubin-specific UDPGT |
| Swissprots | P70691 Q545X2 Q6XL49 |
| Accessions | EDL40122 P70691 AK002629 BAB22243 AY227195 AAP48594 BC138676 AAI38677 BC145969 AAI45970 D87866 BAA13482 NM_013701 NP_038729 |
| Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. |
| Subcellular Location | Microsome {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. |
| Tissue Specificity | Expressed in kidney. {ECO:0000269|PubMed:14672974}. |
| Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450 |