Gene Symbol | Ugt1a2 |
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Entrez Gene | 22236 |
Alt Symbol | UDPGT 1-2, Ugt1 |
Species | Mouse |
Gene Type | protein-coding |
Description | UDP glucuronosyltransferase 1 family, polypeptide A2 |
Other Description | UDP-glucuronosyltransferase 1 family, member 2|UDP-glucuronosyltransferase 1 family, polypeptide A2|UDP-glucuronosyltransferase 1-2|UDP-glucuronosyltransferase 1A2|UDPGT|UGT1*0|UGT1-02|UGT1.2|bilirubin specific|bilirubin-specific UDPGT |
Swissprots | P70691 Q545X2 Q6XL49 |
Accessions | EDL40122 P70691 AK002629 BAB22243 AY227195 AAP48594 BC138676 AAI38677 BC145969 AAI45970 D87866 BAA13482 NM_013701 NP_038729 |
Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. |
Subcellular Location | Microsome {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed in kidney. {ECO:0000269|PubMed:14672974}. |
Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450 |
UGT1A2 CRISPR/Cas9 KO Plasmid (m) - sc-423602 from Santa Cruz Biotechnology
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UGT1A2 HDR Plasmid (m) - sc-423602-HDR from Santa Cruz Biotechnology
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UGT1A2 Double Nickase Plasmid (m) - sc-423602-NIC from Santa Cruz Biotechnology
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UGT1A2 Double Nickase Plasmid (m2) - sc-423602-NIC-2 from Santa Cruz Biotechnology
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UGT1A2 CRISPR Activation Plasmid (m) - sc-423602-ACT from Santa Cruz Biotechnology
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UGT1A2 CRISPR Activation Plasmid (m2) - sc-423602-ACT-2 from Santa Cruz Biotechnology
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UGT1A2 Lentiviral Activation Particles (m) - sc-423602-LAC from Santa Cruz Biotechnology
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UGT1A2 Lentiviral Activation Particles (m2) - sc-423602-LAC-2 from Santa Cruz Biotechnology
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UGT1A2 siRNA (m) - sc-44883 from Santa Cruz Biotechnology
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UGT1A2 shRNA Plasmid (m) - sc-44883-SH from Santa Cruz Biotechnology
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UGT1A2 shRNA (m) Lentiviral Particles - sc-44883-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN43899 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND43899 from Sigma-Aldrich
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UGT1A2 siRNA (Mouse) - CRM4334 from Cohesion Biosciences
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UGT1A2 - MBS829578 from MyBioSource
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shRNA set against Mouse Ugt1a2 (NM_013701.3) - SHH440064 from Creative biogene
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Mouse UGT1A2 siRNA - orb283810 from Biorbyt
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UGT1A2 shRNA Plasmid (Mouse) - CHM4334 from Cohesion Biosciences
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