Gene Symbol |
MAOA
|
Entrez Gene |
101106401
|
Alt Symbol |
-
|
Species |
Sheep
|
Gene Type |
protein-coding
|
Description |
monoamine oxidase A
|
Other Description |
-
|
Swissprots |
O18851
|
Accessions |
AAC16911 XM_004022016 XP_004022065 XM_012158476 XP_012013866
|
Function |
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity). {ECO:0000250}.
|
Subcellular Location |
Mitochondrion outer membrane.
|
Top Pathways |
Dopaminergic synapse, Glycine, serine and threonine metabolism, Alcoholism, Cocaine addiction, Amphetamine addiction
|