Gene Symbol |
Neurog3
|
Entrez Gene |
11925
|
Alt Symbol |
Atoh5, Math4B, bHLHa7, ngn3
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
neurogenin 3
|
Other Description |
NGN-3|Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B)|atonal homolog 5|helix-loop-helix protein mATH-4B|neurogenin-3|protein atonal homolog 5
|
Swissprots |
P70661
|
Accessions |
AAC53029 AAK50058 CAA70366 EDL32112 EDL32113 P70661 AK008017 BAB25411 BC104326 AAI04327 BC104327 AAI04328 NM_009719 NP_033849
|
Function |
Acts as a transcriptional regulator. Together with NKX2- 2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. {ECO:0000269|PubMed:10677506, ECO:0000269|PubMed:19759004}.
|
Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.
|
Top Pathways |
Maturity onset diabetes of the young
|