| Gene Symbol |
WNT3A
|
| Entrez Gene |
395396
|
| Alt Symbol |
WNT-3A, WNT3
|
| Species |
Chicken
|
| Gene Type |
protein-coding
|
| Description |
wingless-type MMTV integration site family, member 3A
|
| Other Description |
Protein Wnt|Wnt-3a homolog|Wnt3a variant 3|protein Wnt-3a|wingless-type MMTV integration site family member 3a|wingless-type MMTV integration site family, member 3
|
| Swissprots |
Q2LMP1 Q9PWH1
|
| Accessions |
BAF49000 BAF49001 Q2LMP1 AB024080 BAA83743 AF109144 AAD19652 CR386781 DQ022307 AAY87456 EF068232 ABK90821 NM_001171601 NP_001165072 NM_204675 NP_990006
|
| Function |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). Isoform 1 regulates chick apical ectodermal ridge formation. {ECO:0000250, ECO:0000269|PubMed:16258938, ECO:0000269|PubMed:17488271}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:16258938}.
|
| Tissue Specificity |
Expressed in cornea. Isoform 1 is expressed in the primitive streak, dorsal neural tube, proximal otic vesicle, the apical ectodermal ridge and the epithelium of feather buds. {ECO:0000269|PubMed:16258938, ECO:0000269|PubMed:17488271}.
|
| Top Pathways |
Wnt signaling pathway, Hedgehog signaling pathway, Melanogenesis
|