Gene Symbol | UCMA |
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Entrez Gene | 221044 |
Alt Symbol | C10orf49, GRP, GRP/UCMA |
Species | Human |
Gene Type | protein-coding |
Description | upper zone of growth plate and cartilage matrix associated |
Other Description | Gla-rich protein|unique cartilage matrix-associated protein |
Swissprots | Q8WVF2 |
Accessions | EAW86296 Q8WVF2 AA628504 BC018068 AAH18068 JX169863 AGH25906 JX169864 AGH25907 JX169865 AGH25908 NM_001303118 NP_001290047 NM_001303119 NP_001290048 NM_145314 NP_660357 |
Function | May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in resting chondrocytes. {ECO:0000269|PubMed:16176871}. |
UCMA CRISPR/Cas9 KO Plasmid (h) - sc-406716 from Santa Cruz Biotechnology
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UCMA HDR Plasmid (h) - sc-406716-HDR from Santa Cruz Biotechnology
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UCMA Double Nickase Plasmid (h) - sc-406716-NIC from Santa Cruz Biotechnology
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UCMA Double Nickase Plasmid (h2) - sc-406716-NIC-2 from Santa Cruz Biotechnology
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UCMA CRISPR Activation Plasmid (h) - sc-406716-ACT from Santa Cruz Biotechnology
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UCMA CRISPR Activation Plasmid (h2) - sc-406716-ACT-2 from Santa Cruz Biotechnology
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UCMA Lentiviral Activation Particles (h) - sc-406716-LAC from Santa Cruz Biotechnology
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UCMA Lentiviral Activation Particles (h2) - sc-406716-LAC-2 from Santa Cruz Biotechnology
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UCMA siRNA (h) - sc-90398 from Santa Cruz Biotechnology
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UCMA shRNA Plasmid (h) - sc-90398-SH from Santa Cruz Biotechnology
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UCMA shRNA (h) Lentiviral Particles - sc-90398-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22441 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02564 from Sigma-Aldrich
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UCMA siRNA (Human) - CRJ6483 from Cohesion Biosciences
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UCMA - MBS8224079 from MyBioSource
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shRNA set against Human UCMA (NM_145314.1) - SHH439828 from Creative biogene
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shRNA set against Human C10orf49(NM_145314.1) - SHG109657 from Creative biogene
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Human UCMA siRNA - orb276984 from Biorbyt
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UCMA shRNA Plasmid (Human) - CHJ6483 from Cohesion Biosciences
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UCMA miRNA 3'UTR clone - MiUTR1H-01007 from Creative biogene
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