Gene Symbol | NDUFB7 |
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Entrez Gene | 4713 |
Alt Symbol | B18, CI-B18 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7|NADH-ubiquinone oxidoreductase B18 subunit|cell adhesion protein SQM1|complex I B18 subunit|complex I-B18 |
Swissprots | Q9UI16 Q6ICN9 P17568 |
Accessions | EAW84436 P17568 AF112200 AAF17188 AF217091 AAF91223 BC002595 AAH02595 BU565399 CB124371 CR450354 CAG29350 DQ891899 ABM82825 DQ895085 ABM86011 M33374 AAA35675 XM_011528039 XP_011526341 NM_004146 NP_004137 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:21310150}; Peripheral membrane protein {ECO:0000269|PubMed:21310150}. Mitochondrion intermembrane space {ECO:0000269|PubMed:21310150}. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB7 CRISPR/Cas9 KO Plasmid (h) - sc-409653 from Santa Cruz Biotechnology
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NDUFB7 HDR Plasmid (h) - sc-409653-HDR from Santa Cruz Biotechnology
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NDUFB7 Double Nickase Plasmid (h) - sc-409653-NIC from Santa Cruz Biotechnology
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NDUFB7 Double Nickase Plasmid (h2) - sc-409653-NIC-2 from Santa Cruz Biotechnology
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NDUFB7 CRISPR Activation Plasmid (h) - sc-409653-ACT from Santa Cruz Biotechnology
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NDUFB7 CRISPR Activation Plasmid (h2) - sc-409653-ACT-2 from Santa Cruz Biotechnology
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NDUFB7 Lentiviral Activation Particles (h) - sc-409653-LAC from Santa Cruz Biotechnology
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NDUFB7 Lentiviral Activation Particles (h2) - sc-409653-LAC-2 from Santa Cruz Biotechnology
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NDUFB7 siRNA (h) - sc-97267 from Santa Cruz Biotechnology
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NDUFB7 shRNA Plasmid (h) - sc-97267-SH from Santa Cruz Biotechnology
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NDUFB7 shRNA (h) Lentiviral Particles - sc-97267-V from Santa Cruz Biotechnology
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NDUFB7 RNAi - H00004713-R01V from Novus Biologicals
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NDUFB7 RNAi - H00004713-R01 from Novus Biologicals
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MISSION® esiRNA - EHU011781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15161 from Sigma-Aldrich
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NDUFB7 siRNA (Human) - CRH3127 from Cohesion Biosciences
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shRNA set against Human NDUFB7 (NM_004146.5) - SHH350780 from Creative biogene
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Human NDUFB7 siRNA - orb263629 from Biorbyt
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NDUFB7 shRNA Plasmid (Human) - CHH3127 from Cohesion Biosciences
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NDUFB7 miRNA 3'UTR clone - MiUTR3H-06310 from Creative biogene
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