Gene Symbol |
YY1AP1
|
Entrez Gene |
55249
|
Alt Symbol |
HCCA1, HCCA2, YAP, YY1AP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
YY1 associated protein 1
|
Other Description |
YY1-associated protein 1|hepatocellular carcinoma susceptibility protein|hepatocellular carcinoma-associated protein 2
|
Swissprots |
Q5VYZ7 B4DMP2 Q8TF04 Q8TEW5 H7BY62 Q5VYZ4 Q96HB6 Q9H869 B0QZ54 Q5VYZ1 Q7L5E2 Q8IXA6 D3DV96 D3DV98 Q9BQ64 B4E0I0 Q7L4C3 Q9NV84
|
Accessions |
EAW53052 EAW53053 EAW53054 EAW53055 EAW53056 EAW53057 EAW53058 EAW53059 EAW53060 Q9H869 AF203474 AAO13249 AF206328 AAL74055 AF466401 AAL75971 AK001737 BAA91871 AK023976 BAB14748 AK125590 AK225883 AK297562 BAG59954 AK298904 BAG61012 AK303046 BAG64166 AK303386 BAG64442 AK303944 BAG64872 AK309701 AK315049 AM393344 CAL38222 AM393852 CAL38727 AY604179 AAT34990 BC001655 AAH01655 BC001843 AAH01843 BC003500 BC008766 AAH08766 BC009358 AAH09358 BC014906 AAH14906 BC025272 BC044887 AAH44887 BG325066 CR749789 CAH18650 DC300265 DC346197 DC388975 DC399389 DC406177 XM_011509721 XP_011508023 XM_011509722 XP_011508024 NM_139119 NP_620830 NM_139120 NM_001198899 NP_001185828 NM_001198900 NP_001185829 NM_001198901 NP_001185830 NM_001198902 NP_001185831 NM_001198903 NP_001185832 NM_001198904 NP_001185833 NM_001198905 NP_001185834 NM_001198906 NP_001185835 NM_018253 NP_060723 NM_139118 NP_620829 NM_139121 NP_620832
|
Function |
Enhances transcription activation by YY1. May play a role in cell cycle regulation. {ECO:0000269|PubMed:14744866, ECO:0000269|PubMed:17541814}.
|
Subcellular Location |
Cytoplasm. Nucleus.
|
Tissue Specificity |
Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas. {ECO:0000269|PubMed:11710830, ECO:0000269|PubMed:12118372, ECO:0000269|PubMed:14744866}.
|