| Gene Symbol |
MAFG
|
| Entrez Gene |
769355
|
| Alt Symbol |
-
|
| Species |
Chicken
|
| Gene Type |
protein-coding
|
| Description |
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
|
| Other Description |
MafG, a bZip nuclear protein structurally related to maf oncoegene product|transcription factor MafG
|
| Swissprots |
Q90889
|
| Accessions |
BAA05939 Q90889 NM_001079489 NP_001072957
|
| Function |
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF- E2. May be involved in signal transduction of extracellular H(+) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus.
|