| Gene Symbol |
FN1
|
| Entrez Gene |
396133
|
| Alt Symbol |
FN
|
| Species |
Chicken
|
| Gene Type |
protein-coding
|
| Description |
fibronectin 1
|
| Other Description |
fibronectin
|
| Swissprots |
P11722 Q90921
|
| Accessions |
AAC41259 P11722 BX932253 BX933838 CR353830 U20386 AAB01062 U21327 AAA73566 V00405 NM_001198712 NP_001185641
|
| Function |
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
| Tissue Specificity |
Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, Regulation of actin cytoskeleton
|