Gene Symbol | Akr1a1 |
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Entrez Gene | 100689106 |
Alt Symbol | Alr |
Species | Hamster |
Gene Type | protein-coding |
Description | aldo-keto reductase family 1, member A1 (aldehyde reductase) |
Other Description | Alcohol dehydrogenase|Aldo-keto reductase family 1 member A1|aldehyde reductase |
Swissprots | O70473 |
Accessions | EGV94590 O70473 AF060820 AAC15760 JI894009 JP058611 XM_003497372 XP_003497420 XM_007622040 XP_007620230 |
Function | Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs (By similarity). {ECO:0000250}. |
Top Pathways | Glycolysis / Gluconeogenesis, Pentose and glucuronate interconversions, Glycerolipid metabolism, Degradation of aromatic compounds |
Recombinant Cricetulus griseus Alcohol dehydrogenase [NADP(+)] - CSB-YP530345DXU CSB-EP530345DXU CSB-BP530345DXU CSB-MP530345DXU from Cusabio
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Alcohol dehydrogenase [NADP (+) ] - MBS1091350 from MyBioSource
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