Gene Symbol | SLC9A9 |
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Entrez Gene | 285195 |
Alt Symbol | AUTS16, NHE9 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 |
Other Description | Na(+)/H(+) exchanger 9|putative protein product of Nbla00118|sodium/hydrogen exchanger 9|sodium/proton exchanger NHE9|solute carrier family 9 (sodium/hydrogen exchanger) |
Swissprots | Q3LIC2 Q5JPI6 Q8IVB4 Q5WA58 Q8NAB9 A6NMQ9 |
Accessions | EAW78950 EAW78951 Q8IVB4 AB075486 BAE45746 AB089794 BAD69592 AI252807 AK092932 BAC04005 AK301816 BAG63263 AK315107 BAG37567 AL832304 CAI46158 AY254100 AAP80573 BC035779 AAH35779 DA387367 DB285312 XM_011512703 XP_011511005 XM_011512704 XP_011511006 NM_173653 NP_775924 |
Function | May act in electroneutral exchange of protons for Na(+) across membranes. Involved in the effusion of Golgi luminal H(+) in exchange for cytosolic cations. Involved in organelle ion homeostasis by contributing to the maintenance of the unique acidic pH values of the Golgi and post-Golgi compartments in the cell. {ECO:0000269|PubMed:15522866}. |
Subcellular Location | Late endosome membrane {ECO:0000269|PubMed:15522866}; Multi-pass membrane protein {ECO:0000269|PubMed:15522866}. |
Tissue Specificity | Ubiquitously expressed in all tissues tested. Expressed at highest levels in heart and skeletal muscle, followed by placenta, kidney, and liver. Expressed in the brain, in the medulla and spinal cord. {ECO:0000269|PubMed:14569117, ECO:0000269|PubMed:15522866}. |
NHE-9 CRISPR/Cas9 KO Plasmid (h) - sc-410416 from Santa Cruz Biotechnology
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NHE-9 HDR Plasmid (h) - sc-410416-HDR from Santa Cruz Biotechnology
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NHE-9 Double Nickase Plasmid (h) - sc-410416-NIC from Santa Cruz Biotechnology
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NHE-9 Double Nickase Plasmid (h2) - sc-410416-NIC-2 from Santa Cruz Biotechnology
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NHE-9 CRISPR Activation Plasmid (h) - sc-410416-ACT from Santa Cruz Biotechnology
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NHE-9 CRISPR Activation Plasmid (h2) - sc-410416-ACT-2 from Santa Cruz Biotechnology
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NHE-9 Lentiviral Activation Particles (h) - sc-410416-LAC from Santa Cruz Biotechnology
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NHE-9 Lentiviral Activation Particles (h2) - sc-410416-LAC-2 from Santa Cruz Biotechnology
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NHE-9 siRNA (h) - sc-77892 from Santa Cruz Biotechnology
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NHE-9 shRNA Plasmid (h) - sc-77892-SH from Santa Cruz Biotechnology
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NHE-9 shRNA (h) Lentiviral Particles - sc-77892-V from Santa Cruz Biotechnology
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SLC9A9 RNAi - H00285195-R01 from Novus Biologicals
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MISSION® esiRNA - EHU010011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2557 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2557 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09366 from Sigma-Aldrich
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SLC9A9 siRNA (Human) - CRJ7075 from Cohesion Biosciences
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SLC9A9 - MBS8220375 from MyBioSource
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shRNA set against Human SLC9A9 (NM_173653.3) - SHH412396 from Creative biogene
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Human SLC9A9 siRNA - orb277576 from Biorbyt
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SLC9A9 shRNA Plasmid (Human) - CHJ7075 from Cohesion Biosciences
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SLC9A9 miRNA 3'UTR clone - MiUTR3H-09970 from Creative biogene
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