| Gene Symbol |
INF2
|
| Entrez Gene |
64423
|
| Alt Symbol |
C14orf151, C14orf173, CMTDIE, FSGS5, pp9484
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
inverted formin, FH2 and WH2 domain containing
|
| Other Description |
HBEAG-binding protein 2 binding protein C|HBEBP2-binding protein C|inverted formin-2
|
| Swissprots |
Q6P1X7 Q86TR7 Q6PK22 Q9BRM1 Q9H6N1 Q69YL8 Q27J81 Q27J83
|
| Accessions |
EAW81871 EAW81872 EAW81873 EAW81874 EAW81875 Q27J81 AF318379 AAL55886 AK025709 BAB15224 AK027105 BAB15659 AK225325 AK290083 BAF82772 AL832905 CAH10628 BC006173 AAH06173 BC008756 AAH08756 BC064828 AAH64828 BC172394 AAI72394 BG335490 BG820892 BI489810 BQ961756 BU538960 BX248757 CAD66564 CD631414 DA500952 DQ395338 ABD59343 DQ395339 ABD59344 DQ395340 ABD59345 DQ499599 ABF54970 XM_005268004 XP_005268061 XM_005268005 XP_005268062 XR_943507 NM_001031714 NP_001026884 NM_022489 NP_071934 NM_032714 NP_116103
|
| Function |
Severs actin filaments and accelerates their polymerization and depolymerization. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000269|PubMed:20023659}.
|
| Tissue Specificity |
Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells. {ECO:0000269|PubMed:20023659}.
|
![Western Blot: INF2 Overexpression Lysate (Adult Normal) [NBL1-08180] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for INF2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1199_INF2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08180-img0002.jpg)