Gene Symbol |
NKG7
|
Entrez Gene |
4818
|
Alt Symbol |
GIG1, GMP-17, p15-TIA-1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
natural killer cell granule protein 7
|
Other Description |
G-CSF-induced gene 1 protein|GIG-1 protein|granule membrane protein 17|granule membrane protein of 17 kDa|natural killer cell group 7 sequence|natural killer cell protein 7|protein NKG7
|
Swissprots |
Q16617
|
Accessions |
AAA18209 AAG32329 EAW72006 EAW72007 EAW72008 Q16617 AI313472 BC015759 AAH15759 DQ895942 ABM86868 EU176419 ABW03870 S69115 AAB30078 XM_005258955 XP_005259012 XM_006723228 XP_006723291 NM_005601 NP_005592
|
Subcellular Location |
Cell membrane {ECO:0000269|PubMed:8570616}; Multi-pass membrane protein {ECO:0000269|PubMed:8570616}. Cytoplasmic granule membrane {ECO:0000269|PubMed:8570616}; Multi- pass membrane protein {ECO:0000269|PubMed:8570616}. Note=Cytoplasmic granules of cytolytic T-lymphocytes, NK cells, and neutrophils.
|
Tissue Specificity |
Expressed in activated T-cells, in kidney, liver, lung and pancreas. Not expressed in brain, heart, or skeletal muscle. Expressed at high levels in TCR gamma delta- expressing CTL clones, and in some TCR alpha beta-expressing CTL clones (both CD4+ and CD8+), but is not expressed in other TCR alpha beta-expressing CTL clones and in cell lines representing B- cells, monocytes, and myeloid cells.
|