| Gene Symbol |
ARID4B
|
| Entrez Gene |
51742
|
| Alt Symbol |
BCAA, BRCAA1, RBBP1L1, RBP1L1, SAP180
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
AT rich interactive domain 4B (RBP1-like)
|
| Other Description |
180 kDa Sin3-associated polypeptide|ARID domain-containing protein 4B|AT-rich interactive domain-containing protein 4B|Rb-binding protein homolog|SIN3A-associated protein 180|breast cancer-associated antigen 1|breast cancer-associated antigen BRCAA1|breast carcinoma-associated antigen|histone deacetylase complex subunit SAP180|retinoblastoma-binding protein 1-like 1|sin3-associated polypeptide p180
|
| Swissprots |
Q9H915 Q86WR4 Q5T2C3 Q5HY99 Q5T2C5 A1L465 Q6P600 Q86UX1 Q5T2C6 Q9NZB6 Q9UF62 Q9Y6E1 Q4LE39 Q5T2C4 Q5T2C2 Q9P2W4 Q9NZG4 Q3MHV4 Q9NYU3
|
| Accessions |
EAW70008 EAW70009 EAW70010 EAW70011 EAW70012 EAW70013 EAW70014 EAW70015 Q4LE39 AB210032 BAE06114 AF083249 AAD41239 AF208045 AAF23433 AF214114 AAF28341 AF227899 AAF36964 AI356277 AI431949 AK023144 BAB14428 AK057552 AL133594 CAB63731 AY220790 AAO63590 BC017800 AAH17800 BC048959 AAH48959 BC062536 AAH62536 BC104632 AAI04633 BC130418 AAI30419 BC143719 BF899710 BX648820 CAI46047 XM_005273160 XP_005273217 XM_006711781 XP_006711844 XM_011544212 XP_011542514 XM_011544213 XP_011542515 XR_949145 NM_001206794 NP_001193723 NM_016374 NP_057458 NM_031371 NP_112739
|
| Function |
Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. {ECO:0000269|PubMed:12724404}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00355}. Cytoplasm {ECO:0000269|PubMed:11481388, ECO:0000269|PubMed:15247124}. Note=Cytoplasmic in breast cancer cells.
|
| Tissue Specificity |
Highly expressed in the testis and in breast, lung, colon, pancreatic and ovarian cancers. Expressed at low levels in the thymus, prostate and ovary. {ECO:0000269|PubMed:11481388, ECO:0000269|PubMed:12724404, ECO:0000269|PubMed:15247124}.
|