Gene Symbol |
XDH
|
Entrez Gene |
396025
|
Alt Symbol |
-
|
Species |
Chicken
|
Gene Type |
protein-coding
|
Description |
xanthine dehydrogenase
|
Other Description |
xanthine dehydrogenase/oxidase
|
Swissprots |
P47990
|
Accessions |
CAW36702 CAW39052 CAW41217 CAW47233 CAW63653 CAW71883 CAW80375 CAW82867 CAW86288 CBC02655 CBC04908 CBC06868 CBC13024 CBC45857 CBC62275 CBC79207 CBC84156 CBC89113 P47990 BX931859 D13221 BAA02502 NM_205127 NP_990458
|
Function |
Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species (By similarity). {ECO:0000250}.
|
Subcellular Location |
Peroxisome {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:6953967}.
|
Tissue Specificity |
Detected in liver (at protein level). {ECO:0000269|PubMed:6953967}.
|
Top Pathways |
Peroxisome, Caffeine metabolism, Purine metabolism, Drug metabolism - other enzymes
|