Gene Symbol | STAP1 |
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Entrez Gene | 26228 |
Alt Symbol | BRDG1, STAP-1 |
Species | Human |
Gene Type | protein-coding |
Description | signal transducing adaptor family member 1 |
Other Description | BCR downstream signaling 1|BCR downstream-signaling protein 1|docking protein BRDG1|signal-transducing adaptor protein 1|signal-transducing adaptor protein-1|stem cell adaptor protein 1 |
Swissprots | Q9ULZ2 B2R980 |
Accessions | AAY40998 EAX05547 EAX05548 Q9ULZ2 AB023483 BAA85311 AK313676 BAG36427 BC014958 AAH14958 BG190230 HQ447234 ADQ31721 XM_005265675 XP_005265732 XM_006714175 XP_006714238 XR_427541 NM_012108 NP_036240 |
Function | In BCR signaling, appears to function as a docking protein acting downstream of TEC and participates in a positive feedback loop by increasing the activity of TEC. {ECO:0000269|PubMed:10518561}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17936702}. Cytoplasm {ECO:0000269|PubMed:17936702}. Mitochondrion {ECO:0000269|PubMed:17936702}. |
BRDG1 CRISPR/Cas9 KO Plasmid (h) - sc-409252 from Santa Cruz Biotechnology
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BRDG1 HDR Plasmid (h) - sc-409252-HDR from Santa Cruz Biotechnology
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BRDG1 Double Nickase Plasmid (h) - sc-409252-NIC from Santa Cruz Biotechnology
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BRDG1 Double Nickase Plasmid (h2) - sc-409252-NIC-2 from Santa Cruz Biotechnology
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BRDG1 CRISPR Activation Plasmid (h) - sc-409252-ACT from Santa Cruz Biotechnology
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BRDG1 CRISPR Activation Plasmid (h2) - sc-409252-ACT-2 from Santa Cruz Biotechnology
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BRDG1 Lentiviral Activation Particles (h) - sc-409252-LAC from Santa Cruz Biotechnology
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BRDG1 Lentiviral Activation Particles (h2) - sc-409252-LAC-2 from Santa Cruz Biotechnology
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BRDG1 siRNA (h) - sc-40370 from Santa Cruz Biotechnology
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BRDG1 shRNA Plasmid (h) - sc-40370-SH from Santa Cruz Biotechnology
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BRDG1 shRNA (h) Lentiviral Particles - sc-40370-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU018201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20696 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20696 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04023 from Sigma-Aldrich
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STAP1 siRNA (Human) - CRH8764 from Cohesion Biosciences
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STAP1 - MBS8217948 from MyBioSource
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shRNA set against Human STAP1 (NM_012108.2) - SHH419228 from Creative biogene
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shRNA set against Human BRDG1(NM_012108.2) - SHL032844 from Creative biogene
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Human STAP1 siRNA - orb269266 from Biorbyt
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STAP1 shRNA Plasmid (Human) - CHH8764 from Cohesion Biosciences
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STAP1 miRNA 3'UTR clone - MiUTR1H-00942 from Creative biogene
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