| Gene Symbol |
KITLG
|
| Entrez Gene |
493937
|
| Alt Symbol |
SCF
|
| Species |
Cat
|
| Gene Type |
protein-coding
|
| Description |
KIT ligand
|
| Other Description |
C-kit ligand|MGF|kit ligand|mast cell growth factor|stem cell factor
|
| Swissprots |
P79169
|
| Accessions |
P79169 D50833 BAA09445 XM_006933913 XP_006933975 XM_006933914 XP_006933976 NM_001009343 NP_001009343
|
| Function |
Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Soluble KIT ligand: Secreted {ECO:0000250}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Melanogenesis, PI3K-Akt signaling pathway, Rap1 signaling pathway
|