Gene Symbol | Ccl5 |
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Entrez Gene | 100135495 |
Alt Symbol | RANTES, SCYA5 |
Species | Guinea Pig |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 5 |
Other Description | C-C motif chemokine 5|SIS-delta|T-cell-specific protein RANTES|small-inducible cytokine A5 |
Swissprots | P97272 O09076 |
Accessions | P97272 AB002662 BAA19604 U77037 AAC53293 NM_001172927 NP_001166398 |
Function | Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells. {ECO:0000250|UniProtKB:P13501}. |
Subcellular Location | Secreted. |
Anti-RANTES antibody - ab189841 from Abcam
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RANTES Antibody - abx104742 from Abbexa
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Monoclonal Antibody to Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) - MAA116Gu21 from Cloud-clone
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Polyclonal Antibody to Regulated On Activation In Normal T-Cell Expressed And Secreted (RANTES) - PAA116Gu01 from Cloud-clone
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