Gene Symbol | WDR19 |
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Entrez Gene | 57728 |
Alt Symbol | ATD5, CED4, DYF-2, IFT144, NPHP13, ORF26, Oseg6, PWDMP, SRTD5 |
Species | Human |
Gene Type | protein-coding |
Description | WD repeat domain 19 |
Other Description | WD repeat membrane protein PWDMP|WD repeat-containing protein 19|intraflagellar transport 144 homolog |
Swissprots | B5MEF2 Q9HCD4 Q9H5S0 Q8N5B4 Q8NEZ3 |
Accessions | EAW92915 EAW92916 EAW92917 EAW92918 EAW92919 EAW92920 EAW92921 Q8NEZ3 AB046858 BAB13464 AK026780 BAB15550 AK122908 AK225588 AK294730 BAG57877 AK296112 BAG58861 AK304161 BAG65048 AK308803 AY029257 AAK38745 BC032578 AAH32578 BC131501 BC172278 AAI72278 XM_011513724 XP_011512026 XM_011513725 XP_011512027 XM_011513726 XP_011512028 XM_011513727 XP_011512029 XM_011513728 XP_011512030 XM_011513729 XP_011512031 XR_925155 NM_025132 NP_079408 |
Function | Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Involved in cilia function and/or assembly (By similarity). {ECO:0000250}. |
Subcellular Location | Cell projection, cilium {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Localizes to photoreceptor connecting cilia, to the base of motile cilia in brain ependymal cells and to the base of and along primary cilia in kidney cells. {ECO:0000250}. |
Tissue Specificity | Some isoforms are tissue-specific. Highly expressed in the prostate. Lower expression in the cerebellum, pituitary gland, fetal lung, and pancreas. In normal prostate, expressed in both basal and luminal epithelial cells. No expression detected in fibromuscular stromal cells, endothelial cells, or infiltrating lymphocytes. Uniformed expression in prostate adenocarcinoma cells. {ECO:0000269|PubMed:12906858}. |
WDR19 CRISPR/Cas9 KO Plasmid (h) - sc-412892 from Santa Cruz Biotechnology
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WDR19 HDR Plasmid (h) - sc-412892-HDR from Santa Cruz Biotechnology
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WDR19 Double Nickase Plasmid (h) - sc-412892-NIC from Santa Cruz Biotechnology
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WDR19 Double Nickase Plasmid (h2) - sc-412892-NIC-2 from Santa Cruz Biotechnology
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WDR19 CRISPR Activation Plasmid (h) - sc-412892-ACT from Santa Cruz Biotechnology
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WDR19 CRISPR Activation Plasmid (h2) - sc-412892-ACT-2 from Santa Cruz Biotechnology
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WDR19 Lentiviral Activation Particles (h) - sc-412892-LAC from Santa Cruz Biotechnology
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WDR19 Lentiviral Activation Particles (h2) - sc-412892-LAC-2 from Santa Cruz Biotechnology
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WDR19 siRNA (h) - sc-88970 from Santa Cruz Biotechnology
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WDR19 shRNA Plasmid (h) - sc-88970-SH from Santa Cruz Biotechnology
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WDR19 shRNA (h) Lentiviral Particles - sc-88970-V from Santa Cruz Biotechnology
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WDR19 RNAi - H00057728-R01 from Novus Biologicals
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MISSION® esiRNA - EHU053811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22810 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22810 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02039 from Sigma-Aldrich
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WDR19 siRNA (Human) - CRJ1665 from Cohesion Biosciences
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WDR19 - MBS8235306 from MyBioSource
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shRNA set against Human WDR19 (NM_025132.3) - SHH445960 from Creative biogene
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shRNA set against Human WDR19(NM_025132.3) - SHL131074 from Creative biogene
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WDR19 shRNA Plasmid (Human) - CHJ1665 from Cohesion Biosciences
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WDR19 miRNA 3'UTR clone - MiUTR1H-11205 from Creative biogene
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