| Gene Symbol |
RNF220
|
| Entrez Gene |
55182
|
| Alt Symbol |
C1orf164
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ring finger protein 220
|
| Other Description |
E3 ubiquitin-protein ligase RNF220
|
| Swissprots |
Q5VTB9 Q4KMX2 E9PCS1 B3KPJ3 B4DLZ9 Q9NVP6
|
| Accessions |
EAX07034 EAX07036 Q5VTB9 AF151080 AAF36166 AK001459 BAA91704 AK025744 AK056424 BAG51705 AK124790 BAG54095 AK225180 AK293411 BAG56918 AK296038 BAG58804 AK297228 BAG59711 BC000279 AAH00279 BC034221 AAH34221 BC062600 BC073835 BC098266 AAH98266 BC098300 AAH98300 BC105790 XM_005270992 XP_005271049 XM_005270993 XP_005271050 XM_005270994 XP_005271051 XM_005270996 XP_005271053 XM_005270997 XP_005271054 XM_006710735 XP_006710798 XM_011541697 XP_011539999 XM_011541698 XP_011540000 XM_011541699 XP_011540001 XM_011541700 XP_011540002 XM_011541701 XP_011540003 XM_011541702 XP_011540004 XM_011541703 XP_011540005 XR_946692 NM_018150 NP_060620
|
| Function |
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658). {ECO:0000250|UniProtKB:Q6PDX6, ECO:0000269|PubMed:25266658}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250|UniProtKB:Q6PDX6}.
|