Gene Symbol | MTMR12 |
---|---|
Entrez Gene | 54545 |
Alt Symbol | 3-PAP, PIP3AP |
Species | Human |
Gene Type | protein-coding |
Description | myotubularin related protein 12 |
Other Description | 3-phosphatase adapter protein|3-phosphatase adapter subunit|myotubularin-related protein 12|phosphatidylinositol 3 phosphate 3-phosphatase adapter subunit|phosphatidylinositol-3 phosphate 3-phosphatase adapter subunit|phosphatidylinositol-3 phosphate 3-phosphatase adaptor subunit|phosphatidylinositol-3-phosphate associated protein |
Swissprots | Q9C0I1 Q69YJ4 Q9NX27 Q6PFW3 Q96QU2 |
Accessions | EAX10786 EAX10787 Q9C0I1 AB051469 BAB21773 AF085901 AK000483 BAA91195 AK000967 AL833231 CAH10604 AY028703 AAK26171 BC057393 AAH57393 DB462159 DB483084 XM_005248313 XP_005248370 XM_011514057 XP_011512359 XM_011514058 XP_011512360 XM_011514059 XP_011512361 XM_011514060 XP_011512362 NM_001040446 NP_001035536 NM_001294343 NP_001281272 NM_001294344 NP_001281273 NM_019061 |
Function | Catalytically inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location. {ECO:0000269|PubMed:11504939, ECO:0000269|PubMed:12847286}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12847286}. Note=Localizes to punctate vesicles when associated with MTM1. |
Tissue Specificity | Ubiquitous with prominent expression in brain, heart, kidney, placenta, and lung. {ECO:0000269|PubMed:11504939}. |
MTMR12 CRISPR/Cas9 KO Plasmid (h) - sc-412306 from Santa Cruz Biotechnology
|
||||||||
MTMR12 HDR Plasmid (h) - sc-412306-HDR from Santa Cruz Biotechnology
|
||||||||
MTMR12 Double Nickase Plasmid (h) - sc-412306-NIC from Santa Cruz Biotechnology
|
||||||||
MTMR12 Double Nickase Plasmid (h2) - sc-412306-NIC-2 from Santa Cruz Biotechnology
|
||||||||
MTMR12 CRISPR Activation Plasmid (h) - sc-412306-ACT from Santa Cruz Biotechnology
|
||||||||
MTMR12 CRISPR Activation Plasmid (h2) - sc-412306-ACT-2 from Santa Cruz Biotechnology
|
||||||||
MTMR12 Lentiviral Activation Particles (h) - sc-412306-LAC from Santa Cruz Biotechnology
|
||||||||
MTMR12 Lentiviral Activation Particles (h2) - sc-412306-LAC-2 from Santa Cruz Biotechnology
|
||||||||
MTMR12 siRNA (h) - sc-91717 from Santa Cruz Biotechnology
|
||||||||
MTMR12 shRNA Plasmid (h) - sc-91717-SH from Santa Cruz Biotechnology
|
||||||||
MTMR12 shRNA (h) Lentiviral Particles - sc-91717-V from Santa Cruz Biotechnology
|
||||||||
MTMR12 RNAi - H00054545-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU023401 from Sigma-Aldrich
|
||||||||
MISSION® esiRNA - EHU088311 from Sigma-Aldrich
|
||||||||
MISSION® Human Phosphatase - SIHP0326 from Sigma-Aldrich
|
||||||||
MISSION® Human Phosphatase - SIHP0327 from Sigma-Aldrich
|
||||||||
MISSION® Human Phosphatase - SIHP0325 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN14717 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14717 from Sigma-Aldrich
|
||||||||
MTMR12 siRNA (Human) - CRJ0128 from Cohesion Biosciences
|
||||||||
shRNA set against Human MTMR12 (NM_001040446.1) - SHH346464 from Creative biogene
|
||||||||
shRNA set against Human MTMR12(NM_001040446.1) - SHH206705 from Creative biogene
|
||||||||
Human MTMR12 siRNA - orb270629 from Biorbyt
|
||||||||
MTMR12 shRNA Plasmid (Human) - CHJ0128 from Cohesion Biosciences
|
||||||||
MTMR12 miRNA 3'UTR clone - MiUTR1H-06514 from Creative biogene
|