Gene Symbol | PFKFB3 |
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Entrez Gene | 5209 |
Alt Symbol | IPFK2, PFK2 |
Species | Human |
Gene Type | protein-coding |
Description | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
Other Description | 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase|6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase|6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3|6PF-2-K/Fru-2,6-P2ase 3|6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme|PFK/FBPase 3|fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase|iPFK-2|inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase|renal carcinoma antigen NY-REN-56 |
Swissprots | B7Z955 O43622 O75902 Q5VX18 Q16875 Q5VX19 Q5VX15 |
Accessions | AAB99795 AAD23989 BAA25289 BAA89351 EAW86397 EAW86398 EAW86399 EAW86400 EAW86401 Q16875 AF056320 AAC62000 AF109735 AAD08818 AI633567 AJ227868 AJ272438 CAC34792 AJ272439 CAC34793 AJ272440 CAC34794 AJ295747 CAC20460 AK094645 AK131307 BAD18473 AK291263 BAF83952 AK303039 BAH13886 AK304450 BAH14191 AL583908 BC037258 BC040482 AAH40482 BC042656 D49817 BAA08624 DA315586 DB068734 DC316967 DC323583 HQ257991 ADR82745 L77662 AAL40083 XM_005252463 XP_005252520 XM_005252464 XP_005252521 XM_011519492 XP_011517794 XM_011519493 XP_011517795 NM_001145443 NP_001138915 NM_001282630 NP_001269559 NM_004566 NP_004557 |
Function | Synthesis and degradation of fructose 2,6-bisphosphate. |
Tissue Specificity | Ubiquitous. |
Top Pathways | AMPK signaling pathway, Fructose and mannose metabolism |
PFK-2 br/pl CRISPR/Cas9 KO Plasmid (h) - sc-404532 from Santa Cruz Biotechnology
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PFK-2 br/pl HDR Plasmid (h) - sc-404532-HDR from Santa Cruz Biotechnology
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PFK-2 br/pl Double Nickase Plasmid (h) - sc-404532-NIC from Santa Cruz Biotechnology
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PFK-2 br/pl Double Nickase Plasmid (h2) - sc-404532-NIC-2 from Santa Cruz Biotechnology
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PFK-2 br/pl CRISPR Activation Plasmid (h) - sc-404532-ACT from Santa Cruz Biotechnology
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PFK-2 br/pl CRISPR Activation Plasmid (h2) - sc-404532-ACT-2 from Santa Cruz Biotechnology
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PFK-2 br/pl Lentiviral Activation Particles (h) - sc-404532-LAC from Santa Cruz Biotechnology
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PFK-2 br/pl Lentiviral Activation Particles (h2) - sc-404532-LAC-2 from Santa Cruz Biotechnology
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PFK-2 br/pl siRNA (h) - sc-44011 from Santa Cruz Biotechnology
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PFK-2 br/pl shRNA Plasmid (h) - sc-44011-SH from Santa Cruz Biotechnology
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PFK-2 br/pl shRNA (h) Lentiviral Particles - sc-44011-V from Santa Cruz Biotechnology
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MISSION® Human Phosphatase - SIHP0398 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0399 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0397 from Sigma-Aldrich
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MISSION® siRNA - SIHK1582 from Sigma-Aldrich
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MISSION® siRNA - SIHK1580 from Sigma-Aldrich
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MISSION® siRNA - SIHK1581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16656 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16656 from Sigma-Aldrich
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PFKFB3 siRNA (Human) - CRH3479 from Cohesion Biosciences
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6 Phosphofructo 2 Kinase RNAi - H00005209-R03 from Novus Biologicals
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shRNA set against Human PFKFB3 (NM_004566.3) - SHH373932 from Creative biogene
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Human PFKFB3 siRNA - orb263981 from Biorbyt
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PFKFB3 shRNA Plasmid (Human) - CHH3479 from Cohesion Biosciences
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PFKFB3 miRNA 3'UTR clone - MiUTR1H-07802 from Creative biogene
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