Gene Symbol | AIF1L |
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Entrez Gene | 83543 |
Alt Symbol | C9orf58, IBA2 |
Species | Human |
Gene Type | protein-coding |
Description | allograft inflammatory factor 1-like |
Other Description | ionized calcium binding adapter molecule 2|ionized calcium-binding adapter molecule 2 |
Swissprots | Q8WU47 Q9BQI0 Q9H9G0 Q8NAX7 B2RBC4 Q6ZR40 |
Accessions | EAW87958 EAW87959 Q9BQI0 AK022845 BAB14269 AK027181 AK057789 AK091912 BAC03770 AK128526 BAC87480 AK300473 BAH13291 AK314600 BAG37171 AL136566 CAB66501 AL833896 CAD38752 AM392853 CAL37731 AM393301 CAL38179 AM393860 CAL38735 AY359067 AAQ89426 BC009826 BC021253 AAH21253 BI766795 BM975905 DA285481 NM_001002260 NM_001185095 NP_001172024 NM_001185096 NP_001172025 NM_031426 NP_113614 NR_033701 |
Function | Actin-binding protein that promotes actin bundling. May neither bind calcium nor depend on calcium for function. {ECO:0000269|PubMed:18699778}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:18699778}. Cell projection, ruffle membrane {ECO:0000269|PubMed:18699778}; Peripheral membrane protein {ECO:0000269|PubMed:18699778}; Cytoplasmic side {ECO:0000269|PubMed:18699778}. Note=Colocalizes with F-actin. Partially relocates to membrane ruffles in response to invading bacteria. |
AIF1L RNAi - H00083543-R02 from Novus Biologicals
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MISSION® esiRNA - EHU154911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2981 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12984 from Sigma-Aldrich
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AIF1L siRNA (Human) - CRJ3123 from Cohesion Biosciences
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IBA2 CRISPR/Cas9 KO Plasmid (h) - sc-416971 from Santa Cruz Biotechnology
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IBA2 HDR Plasmid (h) - sc-416971-HDR from Santa Cruz Biotechnology
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IBA2 Double Nickase Plasmid (h) - sc-416971-NIC from Santa Cruz Biotechnology
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IBA2 Double Nickase Plasmid (h2) - sc-416971-NIC-2 from Santa Cruz Biotechnology
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IBA2 CRISPR Activation Plasmid (h) - sc-416971-ACT from Santa Cruz Biotechnology
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IBA2 CRISPR Activation Plasmid (h2) - sc-416971-ACT-2 from Santa Cruz Biotechnology
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IBA2 Lentiviral Activation Particles (h) - sc-416971-LAC from Santa Cruz Biotechnology
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IBA2 Lentiviral Activation Particles (h2) - sc-416971-LAC-2 from Santa Cruz Biotechnology
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Iba2 siRNA (h) - sc-92620 from Santa Cruz Biotechnology
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Iba2 shRNA Plasmid (h) - sc-92620-SH from Santa Cruz Biotechnology
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Iba2 shRNA (h) Lentiviral Particles - sc-92620-V from Santa Cruz Biotechnology
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AIF1L RNAi - H00083543-R01 from Novus Biologicals
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AIF1L - MBS8211466 from MyBioSource
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shRNA set against Human AIF1L (NM_031426.3) - SHH233906 from Creative biogene
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Human AIF1L siRNA - orb273624 from Biorbyt
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AIF1L shRNA Plasmid (Human) - CHJ3123 from Cohesion Biosciences
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AIF1L miRNA 3'UTR clone - MiUTR4H-TG00230 from Creative biogene
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