Gene Symbol | TBC1D32 |
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Entrez Gene | 221322 |
Alt Symbol | BROMI, C6orf170, C6orf171, bA301B7.2, bA57L9.1, dJ310J6.1 |
Species | Human |
Gene Type | protein-coding |
Description | TBC1 domain family, member 32 |
Other Description | bA301B7.2 (novel protein)|broad-minded homolog|dJ310J6.1 (novel protein)|protein broad-minded |
Swissprots | Q6ZUR7 Q6ZMY4 Q5SZD6 Q5SZM6 Q8NB47 Q96NH3 |
Accessions | EAW48180 EAW48181 EAW48182 Q96NH3 AK055461 BAB70925 AK091554 BAC03694 AK125385 BAC86152 AK126259 AK131446 BAD18591 BX112581 DA109825 DA214223 DB084115 DB216282 XM_005266861 XP_005266918 XM_011535569 XP_011533871 XM_011535570 XP_011533872 XM_011535571 XP_011533873 XM_011535572 XP_011533874 XM_011535573 XP_011533875 XM_011535574 XP_011533876 XM_011535575 XP_011533877 XM_011535576 XP_011533878 XM_011535577 XP_011533879 XM_011535578 XP_011533880 XM_011535579 XP_011533881 XM_011535580 XP_011533882 XM_011535581 XP_011533883 XM_011535582 XP_011533884 XM_011535583 XP_011533885 XM_011535584 XP_011533886 XM_011535585 XP_011533887 XM_011535586 XP_011533888 XR_942343 XR_942345 XR_942346 NM_152730 NP_689943 NR_104452 |
Function | Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell projection, cilium {ECO:0000250}. |
C6orf170 CRISPR/Cas9 KO Plasmid (h) - sc-415125 from Santa Cruz Biotechnology
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C6orf170 HDR Plasmid (h) - sc-415125-HDR from Santa Cruz Biotechnology
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C6orf170 Double Nickase Plasmid (h) - sc-415125-NIC from Santa Cruz Biotechnology
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C6orf170 Double Nickase Plasmid (h2) - sc-415125-NIC-2 from Santa Cruz Biotechnology
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C6orf170 CRISPR Activation Plasmid (h) - sc-415125-ACT from Santa Cruz Biotechnology
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C6orf170 CRISPR Activation Plasmid (h2) - sc-415125-ACT-2 from Santa Cruz Biotechnology
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C6orf170 Lentiviral Activation Particles (h) - sc-415125-LAC from Santa Cruz Biotechnology
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C6orf170 Lentiviral Activation Particles (h2) - sc-415125-LAC-2 from Santa Cruz Biotechnology
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C6orf170 siRNA (h) - sc-95255 from Santa Cruz Biotechnology
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C6orf170 shRNA Plasmid (h) - sc-95255-SH from Santa Cruz Biotechnology
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C6orf170 shRNA (h) Lentiviral Particles - sc-95255-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU093161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5041 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08613 from Sigma-Aldrich
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TBC1D32 siRNA (Human) - CRJ6505 from Cohesion Biosciences
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TBC1D32 - MBS8226438 from MyBioSource
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shRNA set against Human C6orf170 (NM_152730.4) - SHH252241 from Creative biogene
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Human TBC1D32 siRNA - orb277006 from Biorbyt
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TBC1D32 shRNA Plasmid (Human) - CHJ6505 from Cohesion Biosciences
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C6ORF170 miRNA 3'UTR clone - MiUTR1H-01455 from Creative biogene
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