Gene Symbol | DLGAP2 |
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Entrez Gene | 9228 |
Alt Symbol | DAP2, SAPAP2 |
Species | Human |
Gene Type | protein-coding |
Description | discs, large (Drosophila) homolog-associated protein 2 |
Other Description | PSD-95/SAP90-binding protein 2|SAP90/PSD-95-associated protein 2|discs large-associated protein 2|disks large-associated protein 2 |
Swissprots | A1QCF8 O14488 A5D8Y2 O14664 A1QCF9 Q9P1A7 Q9P1A6 |
Accessions | EAW51474 EAW51475 Q9P1A6 AA443942 AA444121 AB000275 BAA23256 AF009204 AAB71661 AF119817 AAF34344 AF119818 AAF34345 AW195368 BC141862 AAI41863 KJ534823 AHW56463 XM_011534761 XP_011533063 XM_011534762 XP_011533064 XM_011534763 XP_011533065 XM_011534764 XP_011533066 XM_011534765 XP_011533067 XM_011547369 XP_011545671 XM_011547370 XP_011545672 XM_011547371 XP_011545673 XM_011547372 XP_011545674 XM_011547373 XP_011545675 XM_011547374 XP_011545676 XM_011547375 XP_011545677 XM_011547376 XP_011545678 NM_001277161 NP_001264090 NM_004745 NP_004736 |
Function | May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. |
Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Postsynaptic density of neuronal cells. {ECO:0000250}. |
Tissue Specificity | Expressed in brain and kidney. |
SAPAP2 CRISPR/Cas9 KO Plasmid (h) - sc-411256 from Santa Cruz Biotechnology
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SAPAP2 HDR Plasmid (h) - sc-411256-HDR from Santa Cruz Biotechnology
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SAPAP2 Double Nickase Plasmid (h) - sc-411256-NIC from Santa Cruz Biotechnology
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SAPAP2 Double Nickase Plasmid (h2) - sc-411256-NIC-2 from Santa Cruz Biotechnology
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SAPAP2 CRISPR Activation Plasmid (h) - sc-411256-ACT from Santa Cruz Biotechnology
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SAPAP2 CRISPR Activation Plasmid (h2) - sc-411256-ACT-2 from Santa Cruz Biotechnology
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SAPAP2 Lentiviral Activation Particles (h) - sc-411256-LAC from Santa Cruz Biotechnology
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SAPAP2 Lentiviral Activation Particles (h2) - sc-411256-LAC-2 from Santa Cruz Biotechnology
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SAPAP2 siRNA (h) - sc-77555 from Santa Cruz Biotechnology
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SAPAP2 shRNA Plasmid (h) - sc-77555-SH from Santa Cruz Biotechnology
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SAPAP2 shRNA (h) Lentiviral Particles - sc-77555-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU079711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7290 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7290 from Sigma-Aldrich
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DLGAP2 siRNA (Human) - CRH6108 from Cohesion Biosciences
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DLGAP2 - MBS8232731 from MyBioSource
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shRNA set against Human DLGAP2(NM_004745.3) - SHH006851 from Creative biogene
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Human DLGAP2 siRNA - orb266610 from Biorbyt
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DLGAP2 shRNA Plasmid (Human) - CHH6108 from Cohesion Biosciences
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DLGAP2 miRNA 3'UTR clone - MiUTR1H-02868 from Creative biogene
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