| Gene Symbol |
LRMP
|
| Entrez Gene |
4033
|
| Alt Symbol |
JAW1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
lymphoid-restricted membrane protein
|
| Other Description |
protein Jaw1
|
| Swissprots |
Q12912 Q8N301 B4E077 A0AVM2
|
| Accessions |
CCF76995 EAW96503 EAW96504 EAW96505 Q12912 AI949664 AK303103 BAG64212 AK303256 BAG64339 AW206014 AW408383 BC029391 AAH29391 BC100277 BC126417 AAI26418 BC144164 BC144165 BC144170 BG505192 BM466207 BQ220483 BQ420905 BU679233 DB135324 HQ258271 ADR83025 U10485 AAA21604 XM_005253370 XP_005253427 XM_005253372 XP_005253429 XM_005253374 XP_005253431 XM_006719076 XP_006719139 XM_011520667 XP_011518969 XM_011520668 XP_011518970 XM_011520669 XP_011518971 XM_011520670 XP_011518972 NM_001204126 NP_001191055 NM_001204127 NP_001191056 NM_006152 NP_006143
|
| Function |
Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion.
|
| Subcellular Location |
Processed lymphoid-restricted membrane protein: Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Expressed at high levels in pre B-cells, mature B-cells and pre T-cells. Expressed at low levels in mature T-cells and plasma B-cells. Expressed in germinal center B-cells, splenic marginal zone cells and B-cell lymphomas. Expressed in neuronal cells in the cerebral cortex, epithelial cells in tonsil, adrenal glands, zymogen-producing cells in the stomach and epithelial cells in seminal vesicles. {ECO:0000269|PubMed:16739114, ECO:0000269|PubMed:8021504}.
|