| Gene Symbol |
Postn
|
| Entrez Gene |
50706
|
| Alt Symbol |
A630052E07Rik, AI747096, OSF-2, Osf2, PLF, PN, peri
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
periostin, osteoblast specific factor
|
| Other Description |
osteoblast specific factor 2 (fasciclin I-like)|osteoblast-specific factor 2|periostin|periostin-like factor
|
| Swissprots |
Q8BMJ6 Q8K1K0 Q62009
|
| Accessions |
EDL35257 EDL35258 EDL35259 EDL35260 EDL35261 Q62009 AK030756 BAC27122 AK042015 AK052220 AK154049 BAE32339 AK163070 AY651928 AAT48882 BC007141 BC031449 AAH31449 BE850247 BF020820 D13664 BAA02835 E05655 KM117171 AIS73059 KM117172 AIS73060 XM_006501653 XP_006501716 XM_006501654 XP_006501717 XM_006501655 XP_006501718 NM_001198765 NP_001185694 NM_001198766 NP_001185695 NM_015784 NP_056599
|
| Function |
Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX. {ECO:0000269|PubMed:10404027, ECO:0000269|PubMed:20181949}.
|
| Subcellular Location |
Golgi apparatus. Secreted, extracellular space, extracellular matrix. Note=Colocalizes with BMP1 in the Golgi.
|
| Tissue Specificity |
Preferentially expressed in periosteum and periodontal ligament. Also expressed in the developing and adult heart. {ECO:0000269|PubMed:10404027, ECO:0000269|PubMed:11335131}.
|
![Western Blot: Periostin Overexpression Lysate (Adult Normal) [NBP2-11089] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Periostin.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2368_Periostin%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-11089-img0001.jpg)