Gene Symbol | SYCE1 |
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Entrez Gene | 93426 |
Alt Symbol | C10orf94, CT76 |
Species | Human |
Gene Type | protein-coding |
Description | synaptonemal complex central element protein 1 |
Other Description | cancer/testis antigen 76 |
Swissprots | Q9BWU4 Q8N0S2 Q9BWU3 B2RC80 |
Accessions | AAK21976 EAW61359 EAW61360 Q8N0S2 AK309935 AK314978 BAG37477 AY027807 AAK14796 AY027808 AAK14797 BC034821 AAH34821 DB053356 DB303602 DB336153 HQ448009 ADQ32490 NM_201564 NM_001143763 NP_001137235 NM_001143764 NP_001137236 NM_130784 NP_570140 |
Function | Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Chromosome. Note=Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE2 in the central elements (By similarity). {ECO:0000250}. |
SYCE1 CRISPR/Cas9 KO Plasmid (h) - sc-413973 from Santa Cruz Biotechnology
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SYCE1 HDR Plasmid (h) - sc-413973-HDR from Santa Cruz Biotechnology
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SYCE1 Double Nickase Plasmid (h) - sc-413973-NIC from Santa Cruz Biotechnology
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SYCE1 Double Nickase Plasmid (h2) - sc-413973-NIC-2 from Santa Cruz Biotechnology
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SYCE1 CRISPR Activation Plasmid (h) - sc-413973-ACT from Santa Cruz Biotechnology
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SYCE1 CRISPR Activation Plasmid (h2) - sc-413973-ACT-2 from Santa Cruz Biotechnology
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SYCE1 Lentiviral Activation Particles (h) - sc-413973-LAC from Santa Cruz Biotechnology
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SYCE1 Lentiviral Activation Particles (h2) - sc-413973-LAC-2 from Santa Cruz Biotechnology
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SYCE1 siRNA (h) - sc-90491 from Santa Cruz Biotechnology
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SYCE1 shRNA Plasmid (h) - sc-90491-SH from Santa Cruz Biotechnology
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SYCE1 shRNA (h) Lentiviral Particles - sc-90491-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU114451 from Sigma-Aldrich
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MISSION® esiRNA - EHU004071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20873 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20873 from Sigma-Aldrich
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SYCE1 siRNA (Human) - CRJ4207 from Cohesion Biosciences
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SYCE1 - MBS827307 from MyBioSource
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shRNA set against Human SYCE1 (NM_001143763.1) - SHH421456 from Creative biogene
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Human SYCE1 siRNA - orb274708 from Biorbyt
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SYCE1 shRNA Plasmid (Human) - CHJ4207 from Cohesion Biosciences
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