| Gene Symbol |
COL6A5
|
| Entrez Gene |
256076
|
| Alt Symbol |
COL29A1, VWA4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
collagen, type VI, alpha 5
|
| Other Description |
collagen alpha-5(VI) chain|collagen, type XXIX, alpha 1|von Willebrand factor A domain-containing protein 4
|
| Swissprots |
Q8NA36 A9J6L4 A9J6M1 Q6ZW26 A9J6L2 B5MEA7 A9J6L7 A9J6M0 A8TX70 A9J6M2 A9J6L6
|
| Accessions |
A8TX70 EAW79224 AI743837 AK093199 BAC04092 AK123718 BAC85681 AM906078 CAP19997 AM906079 CAP19998 AM906080 CAP19999 AM906081 CAP20000 AM906082 CAP20001 AM906083 CAP20002 AM906084 CAP20003 EU085556 ABW81241 XM_011512621 XP_011510923 XM_011512622 XP_011510924 XM_011512623 XP_011510925 NM_001278298 NP_001265227 NM_153264 NP_694996 NR_022012
|
| Function |
Collagen VI acts as a cell-binding protein. {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Deposed in the extracellular matrix of skeletal muscle. {ECO:0000250}.
|
| Tissue Specificity |
Expressed in skin, followed by lung, small intestine, colon and testis. In skin, it is expressed in the epidermis with strongest staining in suprabasal viable layers. In ATOD patients, it is absent in the most differentiated upper spinous and granular layers (at protein level). {ECO:0000269|PubMed:17850181}.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, Protein digestion and absorption, PI3K-Akt signaling pathway
|
