Gene Symbol | COCH |
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Entrez Gene | 1690 |
Alt Symbol | COCH-5B2, COCH5B2, DFNA9 |
Species | Human |
Gene Type | protein-coding |
Description | cochlin |
Other Description | coagulation factor C homolog, cochlin (Limulus polyphemus) |
Swissprots | Q96IU6 O43405 A8K9K9 D3DS84 |
Accessions | AAW82432 EAW65963 EAW65964 EAW65965 O43405 AF006740 AAC39545 AK123362 BAG53895 AK130273 BAC85316 AK292724 BAF85413 AW629100 AY358900 AAQ89259 BC000640 BC007230 AAH07230 BC018827 U09203 XM_011536539 XP_011534841 NM_001135058 NP_001128530 NM_004086 NP_004077 |
Function | Plays a role in the control of cell shape and motility in the trabecular meshwork. {ECO:0000269|PubMed:21886777}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:12843317, ECO:0000269|PubMed:22610276}. |
Tissue Specificity | Expressed in inner ear structures; the cochlea and the vestibule. |
Cochlin CRISPR/Cas9 KO Plasmid (h) - sc-405944 from Santa Cruz Biotechnology
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Cochlin HDR Plasmid (h) - sc-405944-HDR from Santa Cruz Biotechnology
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Cochlin Double Nickase Plasmid (h) - sc-405944-NIC from Santa Cruz Biotechnology
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Cochlin Double Nickase Plasmid (h2) - sc-405944-NIC-2 from Santa Cruz Biotechnology
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Cochlin CRISPR Activation Plasmid (h) - sc-405944-ACT from Santa Cruz Biotechnology
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Cochlin CRISPR Activation Plasmid (h2) - sc-405944-ACT-2 from Santa Cruz Biotechnology
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Cochlin Lentiviral Activation Particles (h) - sc-405944-LAC from Santa Cruz Biotechnology
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Cochlin Lentiviral Activation Particles (h2) - sc-405944-LAC-2 from Santa Cruz Biotechnology
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Cochlin siRNA (h) - sc-60427 from Santa Cruz Biotechnology
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Cochlin shRNA Plasmid (h) - sc-60427-SH from Santa Cruz Biotechnology
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Cochlin shRNA (h) Lentiviral Particles - sc-60427-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU029571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2192 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2192 from Sigma-Aldrich
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COCH siRNA (Human) - CRH1189 from Cohesion Biosciences
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COCH - MBS8212159 from MyBioSource
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Cochlin CRISPR/Cas9 KO Plasmid (h2) - sc-405944-KO-2 from Santa Cruz Biotechnology
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Cochlin HDR Plasmid (h2) - sc-405944-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human COCH (NM_004086.2) - SHH266885 from Creative biogene
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Human COCH siRNA - orb261691 from Biorbyt
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COCH shRNA Plasmid (Human) - CHH1189 from Cohesion Biosciences
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COCH miRNA 3'UTR clone - MiUTR3H-05767 from Creative biogene
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COCH miRNA 3'UTR clone - MiUTR3H-05768 from Creative biogene
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